diff --git a/drivers/pinmux/stm32/pinmux_stm32f4.h b/drivers/pinmux/stm32/pinmux_stm32f4.h
index 516af25d32b..a0f72ee987a 100644
--- a/drivers/pinmux/stm32/pinmux_stm32f4.h
+++ b/drivers/pinmux/stm32/pinmux_stm32f4.h
@@ -267,6 +267,8 @@
 
 #define STM32F4_PINMUX_FUNC_PC10_USART3_TX  \
 	(STM32_PINMUX_ALT_FUNC_7 | STM32_PUSHPULL_PULLUP)
+#define STM32F4_PINMUX_FUNC_PC10_UART4_TX  \
+	(STM32_PINMUX_ALT_FUNC_8 | STM32_PUSHPULL_PULLUP)
 
 #define STM32F4_PINMUX_FUNC_PC11_USART3_RX  \
 	(STM32_PINMUX_ALT_FUNC_7 | STM32_PUSHPULL_NOPULL)
diff --git a/dts/arm/st/f4/stm32f4-pinctrl.dtsi b/dts/arm/st/f4/stm32f4-pinctrl.dtsi
index a313c22b23f..54796f25dfe 100644
--- a/dts/arm/st/f4/stm32f4-pinctrl.dtsi
+++ b/dts/arm/st/f4/stm32f4-pinctrl.dtsi
@@ -45,6 +45,18 @@
 					tx = <STM32_PIN_PD8 (STM32_PINMUX_ALT_FUNC_7 | STM32_PUSHPULL_NOPULL)>;
 				};
 			};
+			uart4_pins_a: uart4_a {
+				rx_tx {
+					rx = <STM32_PIN_PA1 (STM32_PINMUX_ALT_FUNC_8 | STM32_PUPDR_NO_PULL)>;
+					tx = <STM32_PIN_PA0 (STM32_PINMUX_ALT_FUNC_8 | STM32_PUSHPULL_NOPULL)>;
+				};
+			};
+			uart4_pins_b: uart4_b {
+				rx_tx {
+					rx = <STM32_PIN_PC11 (STM32_PINMUX_ALT_FUNC_8 | STM32_PUPDR_NO_PULL)>;
+					tx = <STM32_PIN_PC10 (STM32_PINMUX_ALT_FUNC_8 | STM32_PUSHPULL_NOPULL)>;
+				};
+			};
 			usart6_pins_a: usart6_a {
 				rx_tx {
 					rx = <STM32_PIN_PC7 (STM32_PINMUX_ALT_FUNC_8 | STM32_PUPDR_NO_PULL)>;
diff --git a/dts/arm/st/f4/stm32f4.dtsi b/dts/arm/st/f4/stm32f4.dtsi
index 63c39592397..c97786b25ce 100644
--- a/dts/arm/st/f4/stm32f4.dtsi
+++ b/dts/arm/st/f4/stm32f4.dtsi
@@ -133,6 +133,15 @@
 			label = "UART_2";
 		};
 
+		uart4: serial@40004c00 {
+			compatible = "st,stm32-usart", "st,stm32-uart";
+			reg = <0x40004C00 0x400>;
+			clocks = <&rcc STM32_CLOCK_BUS_APB1 0x00080000>;
+			interrupts = <52 0>;
+			status = "disabled";
+			label = "UART_4";
+		};
+
 		usart6: serial@40011400 {
 			compatible = "st,stm32-usart", "st,stm32-uart";
 			reg = <0x40011400 0x400>;
diff --git a/soc/arm/st_stm32/stm32f4/dts_fixup.h b/soc/arm/st_stm32/stm32f4/dts_fixup.h
index 6176f757a1a..0830718ed75 100644
--- a/soc/arm/st_stm32/stm32f4/dts_fixup.h
+++ b/soc/arm/st_stm32/stm32f4/dts_fixup.h
@@ -125,6 +125,14 @@
 #define DT_UART_STM32_USART_3_CLOCK_BITS     DT_ST_STM32_USART_40004800_CLOCK_BITS
 #define DT_UART_STM32_USART_3_CLOCK_BUS      DT_ST_STM32_USART_40004800_CLOCK_BUS
 
+#define DT_UART_STM32_UART_4_BASE_ADDRESS   DT_ST_STM32_USART_40004C00_BASE_ADDRESS
+#define DT_UART_STM32_UART_4_BAUD_RATE      DT_ST_STM32_USART_40004C00_CURRENT_SPEED
+#define DT_UART_STM32_UART_4_IRQ_PRI        DT_ST_STM32_USART_40004C00_IRQ_0_PRIORITY
+#define DT_UART_STM32_UART_4_NAME           DT_ST_STM32_USART_40004C00_LABEL
+#define DT_UART_4_IRQ                              DT_ST_STM32_USART_40004C00_IRQ_0
+#define DT_UART_STM32_UART_4_CLOCK_BITS     DT_ST_STM32_USART_40004C00_CLOCK_BITS
+#define DT_UART_STM32_UART_4_CLOCK_BUS      DT_ST_STM32_USART_40004C00_CLOCK_BUS
+
 #define DT_UART_STM32_USART_6_NAME           DT_ST_STM32_USART_40011400_LABEL
 #define DT_UART_STM32_USART_6_BASE_ADDRESS   DT_ST_STM32_USART_40011400_BASE_ADDRESS
 #define DT_UART_STM32_USART_6_BAUD_RATE      DT_ST_STM32_USART_40011400_CURRENT_SPEED