diff --git a/boards/arm/stm32l562e_dk/Kconfig.defconfig b/boards/arm/stm32l562e_dk/Kconfig.defconfig
index 1a631d7c510..c35d42fa046 100644
--- a/boards/arm/stm32l562e_dk/Kconfig.defconfig
+++ b/boards/arm/stm32l562e_dk/Kconfig.defconfig
@@ -8,4 +8,28 @@ if BOARD_STM32L562E_DK
 config BOARD
 	default "stm32l562e_dk"
 
+if BT
+
+config SPI
+	default y
+
+choice BT_HCI_BUS_TYPE
+	default BT_SPI
+endchoice
+
+config BT_SPI_BLUENRG
+	default y
+
+config BT_BLUENRG_ACI
+	default y
+
+# Disable Flow control
+config BT_HCI_ACL_FLOW_CONTROL
+	default n
+
+config BT_HCI_VS_EXT
+	default n
+
+endif # BT
+
 endif # BOARD_STM32L562E_DK
diff --git a/boards/arm/stm32l562e_dk/doc/index.rst b/boards/arm/stm32l562e_dk/doc/index.rst
index f1399c4dea1..6e4ae4589ca 100644
--- a/boards/arm/stm32l562e_dk/doc/index.rst
+++ b/boards/arm/stm32l562e_dk/doc/index.rst
@@ -164,6 +164,8 @@ The Zephyr stm32l562e_dk board configuration supports the following hardware fea
 +-----------+------------+-------------------------------------+
 | I2C       | on-chip    | i2c                                 |
 +-----------+------------+-------------------------------------+
+| SPI       | on-chip    | spi                                 |
++-----------+------------+-------------------------------------+
 
 Other hardware features are not yet supported on this Zephyr port.
 
@@ -184,6 +186,7 @@ Default Zephyr Peripheral Mapping:
 
 - USART_1 TX/RX : PA9/PA10
 - I2C_1 SCL/SDA : PB6/PB7
+- SPI_1 SCK/MISO/MOSI : PG2/PG3/PG4 (BT SPI bus)
 - USER_PB : PC13
 - LD10 : PG12
 
diff --git a/boards/arm/stm32l562e_dk/stm32l562e_dk_common.dtsi b/boards/arm/stm32l562e_dk/stm32l562e_dk_common.dtsi
index c1cdad6c36e..d083f9e759e 100644
--- a/boards/arm/stm32l562e_dk/stm32l562e_dk_common.dtsi
+++ b/boards/arm/stm32l562e_dk/stm32l562e_dk_common.dtsi
@@ -48,3 +48,18 @@
 		label = "LSM6DSO";
 	};
 };
+
+&spi1 {
+	pinctrl-0 = <&spi1_sck_pg2 &spi1_miso_pg3 &spi1_mosi_pg4>;
+	cs-gpios = <&gpiog 5 (GPIO_ACTIVE_HIGH | GPIO_PULL_UP)>;
+	status = "okay";
+
+	spbtle-rf@0 {
+		compatible = "zephyr,bt-hci-spi";
+		reg = <0>;
+		irq-gpios = <&gpiog 6 (GPIO_ACTIVE_HIGH | GPIO_PULL_DOWN)>;
+		reset-gpios = <&gpiog 8 (GPIO_ACTIVE_LOW | GPIO_PULL_UP)>;
+		spi-max-frequency = <2000000>;
+		label = "SPBTLE-RF";
+	};
+};