diff --git a/drivers/ieee802154/ieee802154_rf2xx.c b/drivers/ieee802154/ieee802154_rf2xx.c
index f36edda63bf..ea0eee56757 100644
--- a/drivers/ieee802154/ieee802154_rf2xx.c
+++ b/drivers/ieee802154/ieee802154_rf2xx.c
@@ -841,44 +841,14 @@ static inline int configure_gpios(const struct device *dev)
 
 static inline int configure_spi(const struct device *dev)
 {
-	struct rf2xx_context *ctx = dev->data;
 	const struct rf2xx_config *conf = dev->config;
 
-	/* Get SPI Driver Instance*/
-	ctx->spi = device_get_binding(conf->spi.devname);
-	if (!ctx->spi) {
-		LOG_ERR("Failed to get instance of %s device",
-			conf->spi.devname);
-
+	if (!spi_is_ready(&conf->spi)) {
+		LOG_ERR("SPI bus %s is not ready",
+			conf->spi.bus->name);
 		return -ENODEV;
 	}
 
-	/* Apply SPI Config: 8-bit, MSB First, MODE-0 */
-	ctx->spi_cfg.operation = SPI_WORD_SET(8) |
-				 SPI_TRANSFER_MSB;
-	ctx->spi_cfg.slave = conf->spi.addr;
-	ctx->spi_cfg.frequency = conf->spi.freq;
-	ctx->spi_cfg.cs = NULL;
-
-	/*
-	 * Get SPI Chip Select Instance
-	 *
-	 * This is an optinal feature configured on DTS. Some SPI controllers
-	 * automatically set CS line by device slave address. Check your SPI
-	 * device driver to understand if you need this option enabled.
-	 */
-	ctx->spi_cs.gpio_dev = device_get_binding(conf->spi.cs.devname);
-	if (ctx->spi_cs.gpio_dev) {
-		ctx->spi_cs.gpio_pin = conf->spi.cs.pin;
-		ctx->spi_cs.gpio_dt_flags = conf->spi.cs.flags;
-		ctx->spi_cs.delay = 0U;
-
-		ctx->spi_cfg.cs = &ctx->spi_cs;
-
-		LOG_DBG("SPI GPIO CS configured on %s:%u",
-			conf->spi.cs.devname, conf->spi.cs.pin);
-	}
-
 	return 0;
 }
 
@@ -981,18 +951,6 @@ static struct ieee802154_radio_api rf2xx_radio_api = {
 	UTIL_AND(DT_INST_NODE_HAS_PROP(n, gpio_pha),			\
 		 DT_INST_GPIO_FLAGS(n, gpio_pha))
 
-#define DRV_INST_SPI_DEV_CS_GPIOS_LABEL(n)				\
-	UTIL_AND(DT_INST_SPI_DEV_HAS_CS_GPIOS(n),			\
-		 DT_INST_SPI_DEV_CS_GPIOS_LABEL(n))
-
-#define DRV_INST_SPI_DEV_CS_GPIOS_PIN(n)				\
-	UTIL_AND(DT_INST_SPI_DEV_HAS_CS_GPIOS(n),			\
-		 DT_INST_SPI_DEV_CS_GPIOS_PIN(n))
-
-#define DRV_INST_SPI_DEV_CS_GPIOS_FLAGS(n)				\
-	UTIL_AND(DT_INST_SPI_DEV_HAS_CS_GPIOS(n),			\
-		 DT_INST_SPI_DEV_CS_GPIOS_FLAGS(n))
-
 #define DRV_INST_LOCAL_MAC_ADDRESS(n)					\
 	UTIL_AND(DT_INST_NODE_HAS_PROP(n, local_mac_address),		\
 		 UTIL_AND(DT_INST_PROP_LEN(n, local_mac_address) == 8,	\
@@ -1023,12 +981,8 @@ static struct ieee802154_radio_api rf2xx_radio_api = {
 		.clkm.pin = DRV_INST_GPIO_PIN(n, clkm_gpios),		\
 		.clkm.flags = DRV_INST_GPIO_FLAGS(n, clkm_gpios),	\
 									\
-		.spi.devname = DT_INST_BUS_LABEL(n),			\
-		.spi.addr = DT_INST_REG_ADDR(n),			\
-		.spi.freq = DT_INST_PROP(n, spi_max_frequency),		\
-		.spi.cs.devname = DRV_INST_SPI_DEV_CS_GPIOS_LABEL(n),	\
-		.spi.cs.pin = DRV_INST_SPI_DEV_CS_GPIOS_PIN(n),		\
-		.spi.cs.flags = DRV_INST_SPI_DEV_CS_GPIOS_FLAGS(n),	\
+		.spi = SPI_DT_SPEC_INST_GET(n, SPI_WORD_SET(8) |	\
+				 SPI_TRANSFER_MSB, 0),			\
 	}
 
 #define IEEE802154_RF2XX_DEVICE_DATA(n)                                 \
diff --git a/drivers/ieee802154/ieee802154_rf2xx.h b/drivers/ieee802154/ieee802154_rf2xx.h
index 2b7ef666a71..4dfe9a4f9e0 100644
--- a/drivers/ieee802154/ieee802154_rf2xx.h
+++ b/drivers/ieee802154/ieee802154_rf2xx.h
@@ -80,13 +80,6 @@ struct rf2xx_dt_gpio_t {
 	uint32_t flags;
 };
 
-struct rf2xx_dt_spi_t {
-	const char *devname;
-	uint32_t freq;
-	uint32_t addr;
-	struct rf2xx_dt_gpio_t cs;
-};
-
 struct rf2xx_config {
 	struct rf2xx_dt_gpio_t irq;
 	struct rf2xx_dt_gpio_t reset;
@@ -94,7 +87,7 @@ struct rf2xx_config {
 	struct rf2xx_dt_gpio_t dig2;
 	struct rf2xx_dt_gpio_t clkm;
 
-	struct rf2xx_dt_spi_t spi;
+	struct spi_dt_spec spi;
 
 	uint8_t inst;
 	uint8_t has_mac;
@@ -111,10 +104,6 @@ struct rf2xx_context {
 	const struct device *dig2_gpio;
 	const struct device *clkm_gpio;
 
-	const struct device *spi;
-	struct spi_config spi_cfg;
-	struct spi_cs_control spi_cs;
-
 	struct gpio_callback irq_cb;
 
 	struct k_thread trx_thread;
diff --git a/drivers/ieee802154/ieee802154_rf2xx_iface.c b/drivers/ieee802154/ieee802154_rf2xx_iface.c
index 2f8ee044d96..a6d7d921b78 100644
--- a/drivers/ieee802154/ieee802154_rf2xx_iface.c
+++ b/drivers/ieee802154/ieee802154_rf2xx_iface.c
@@ -56,7 +56,7 @@ void rf2xx_iface_phy_tx_start(const struct device *dev)
 uint8_t rf2xx_iface_reg_read(const struct device *dev,
 			     uint8_t addr)
 {
-	const struct rf2xx_context *ctx = dev->data;
+	const struct rf2xx_config *conf = dev->config;
 	uint8_t status;
 	uint8_t regval = 0;
 
@@ -85,7 +85,7 @@ uint8_t rf2xx_iface_reg_read(const struct device *dev,
 		.count = 2
 	};
 
-	if (spi_transceive(ctx->spi, &ctx->spi_cfg, &tx, &rx) != 0) {
+	if (spi_transceive_dt(&conf->spi, &tx, &rx) != 0) {
 		LOG_ERR("Failed to exec rf2xx_reg_read CMD at address %d",
 			addr);
 	}
@@ -100,7 +100,7 @@ void rf2xx_iface_reg_write(const struct device *dev,
 			   uint8_t addr,
 			   uint8_t data)
 {
-	const struct rf2xx_context *ctx = dev->data;
+	const struct rf2xx_config *conf = dev->config;
 	uint8_t status;
 
 	addr |= RF2XX_RF_CMD_REG_W;
@@ -128,7 +128,7 @@ void rf2xx_iface_reg_write(const struct device *dev,
 		.count = 1
 	};
 
-	if (spi_transceive(ctx->spi, &ctx->spi_cfg, &tx, &rx) != 0) {
+	if (spi_transceive_dt(&conf->spi, &tx, &rx) != 0) {
 		LOG_ERR("Failed to exec rf2xx_reg_write at address %d",
 			addr);
 	}
@@ -171,7 +171,7 @@ void rf2xx_iface_frame_read(const struct device *dev,
 			    uint8_t *data,
 			    uint8_t length)
 {
-	const struct rf2xx_context *ctx = dev->data;
+	const struct rf2xx_config *conf = dev->config;
 	uint8_t cmd = RF2XX_RF_CMD_FRAME_R;
 
 	const struct spi_buf tx_buf = {
@@ -191,7 +191,7 @@ void rf2xx_iface_frame_read(const struct device *dev,
 		.count = 1
 	};
 
-	if (spi_transceive(ctx->spi, &ctx->spi_cfg, &tx, &rx) != 0) {
+	if (spi_transceive_dt(&conf->spi, &tx, &rx) != 0) {
 		LOG_ERR("Failed to exec rf2xx_frame_read PHR");
 	}
 
@@ -203,7 +203,7 @@ void rf2xx_iface_frame_write(const struct device *dev,
 			     uint8_t *data,
 			     uint8_t length)
 {
-	const struct rf2xx_context *ctx = dev->data;
+	const struct rf2xx_config *conf = dev->config;
 	uint8_t cmd = RF2XX_RF_CMD_FRAME_W;
 	uint8_t status;
 	uint8_t phr;
@@ -242,7 +242,7 @@ void rf2xx_iface_frame_write(const struct device *dev,
 		.count = 1
 	};
 
-	if (spi_transceive(ctx->spi, &ctx->spi_cfg, &tx, &rx) != 0) {
+	if (spi_transceive_dt(&conf->spi, &tx, &rx) != 0) {
 		LOG_ERR("Failed to exec rf2xx_frame_write");
 	}
 
@@ -255,7 +255,7 @@ void rf2xx_iface_sram_read(const struct device *dev,
 			    uint8_t *data,
 			    uint8_t length)
 {
-	const struct rf2xx_context *ctx = dev->data;
+	const struct rf2xx_config *conf = dev->config;
 	uint8_t cmd = RF2XX_RF_CMD_SRAM_R;
 	uint8_t status[2];
 
@@ -288,7 +288,7 @@ void rf2xx_iface_sram_read(const struct device *dev,
 		.count = 2
 	};
 
-	if (spi_transceive(ctx->spi, &ctx->spi_cfg, &tx, &rx) != 0) {
+	if (spi_transceive_dt(&conf->spi, &tx, &rx) != 0) {
 		LOG_ERR("Failed to exec rf2xx_sram_read");
 	}