diff --git a/cmake/dts.cmake b/cmake/dts.cmake
index e203d467d55..e458338df31 100644
--- a/cmake/dts.cmake
+++ b/cmake/dts.cmake
@@ -23,6 +23,8 @@ set(EDT_PICKLE                  ${PROJECT_BINARY_DIR}/edt.pickle)
 set(DEVICETREE_UNFIXED_H        ${PROJECT_BINARY_DIR}/include/generated/devicetree_unfixed.h)
 set(DEVICE_EXTERN_H             ${PROJECT_BINARY_DIR}/include/generated/device_extern.h)
 set(DTS_POST_CPP                ${PROJECT_BINARY_DIR}/${BOARD}.dts.pre.tmp)
+# A list of generally accepted vendor prefixes.
+set_ifndef(VENDOR_PREFIXES      ${ZEPHYR_BASE}/dts/bindings/vendor-prefixes.txt)
 
 set_ifndef(DTS_SOURCE ${BOARD_DIR}/${BOARD}.dts)
 
@@ -228,6 +230,7 @@ if(SUPPORTS_DTS)
   --device-header-out ${DEVICE_EXTERN_H}
   --dts-out ${ZEPHYR_DTS} # As a debugging aid
   --edt-pickle-out ${EDT_PICKLE}
+  --vendor-prefixes ${VENDOR_PREFIXES}
   ${EXTRA_GEN_DEFINES_ARGS}
   )
 
diff --git a/scripts/dts/gen_defines.py b/scripts/dts/gen_defines.py
index 498894907ef..42592cb8e57 100755
--- a/scripts/dts/gen_defines.py
+++ b/scripts/dts/gen_defines.py
@@ -57,6 +57,11 @@ def main():
 
     setup_edtlib_logging()
 
+    if args.vendor_prefixes:
+        vendor_prefixes = edtlib.load_vendor_prefixes_txt(args.vendor_prefixes)
+    else:
+        vendor_prefixes = None
+
     try:
         edt = edtlib.EDT(args.dts, args.bindings_dirs,
                          # Suppress this warning if it's suppressed in dtc
@@ -65,7 +70,8 @@ def main():
                          default_prop_types=True,
                          infer_binding_for_paths=["/zephyr,user"],
                          err_on_deprecated_properties=
-                         args.err_on_deprecated_properties)
+                         args.err_on_deprecated_properties,
+                         vendor_prefixes=vendor_prefixes)
     except edtlib.EDTError as e:
         sys.exit(f"devicetree error: {e}")
 
@@ -209,6 +215,8 @@ def parse_args():
                         help="path to write device struct extern header to")
     parser.add_argument("--edt-pickle-out",
                         help="path to write pickled edtlib.EDT object to")
+    parser.add_argument("--vendor-prefixes",
+                        help="vendor-prefixes.txt path; used for validation")
     parser.add_argument("--err-on-deprecated-properties", action="store_true",
                         help="if set, deprecated property usage is an error")