diff --git a/drivers/clock_control/clock_stm32l0_l1.c b/drivers/clock_control/clock_stm32l0_l1.c
index 2915bb6a03b..a62c743341d 100644
--- a/drivers/clock_control/clock_stm32l0_l1.c
+++ b/drivers/clock_control/clock_stm32l0_l1.c
@@ -38,7 +38,9 @@ void config_pll_init(LL_UTILS_PLLInitTypeDef *pllinit)
  */
 void config_enable_default_clocks(void)
 {
-#if defined(CONFIG_EXTI_STM32) || defined(CONFIG_USB_DC_STM32)
+#if defined(CONFIG_EXTI_STM32) || defined(CONFIG_USB_DC_STM32) || \
+	(defined(CONFIG_SOC_SERIES_STM32L0X) &&			  \
+	 defined(CONFIG_ENTROPY_STM32_RNG))
 	/* Enable System Configuration Controller clock. */
 	LL_APB2_GRP1_EnableClock(LL_APB2_GRP1_PERIPH_SYSCFG);
 #endif