diff --git a/scripts/dts/gen_defines.py b/scripts/dts/gen_defines.py
index 7ed55ab3bf1..a302d538364 100755
--- a/scripts/dts/gen_defines.py
+++ b/scripts/dts/gen_defines.py
@@ -62,6 +62,7 @@ def main():
             flash_area_num += 1
 
         if node.enabled and node.matching_compat:
+            augment_node(node)
             write_regs(node)
             write_irqs(node)
             write_props(node)
@@ -109,6 +110,86 @@ def parse_args():
     return parser.parse_args()
 
 
+def augment_node(node):
+    # Augment an EDT node with these zephyr-specific attributes, which
+    # are used to generate macros from it:
+    #
+    # - z_primary_ident: a primary node identifier based on the node's
+    #   compatible, plus information from its unit address (or its
+    #   parent's unit address) or its name, and/or its bus.
+    #
+    # - z_other_idents: a list of other identifiers for the node,
+    #   besides z_primary_ident.
+    #
+    # - z_idents: a list of all identifiers, containing the primary and other
+    #   identifiers in that order.
+    #
+    # The z_other_idents list contains the following other attributes,
+    # concatenated in this order:
+    #
+    # - z_inst_idents: node identifiers based on the index of the node
+    #   within the EDT list of nodes for each compatible, e.g.:
+    #   ["INST_3_<NODE's_COMPAT>",
+    #    "INST_2_<NODE's_OTHER_COMPAT>"]
+    #
+    # - z_alias_idents: node identifiers based on any /aliases pointing to
+    #   the node in the devicetree source, e.g.:
+    #   ["DT_ALIAS_<NODE's_ALIAS_NAME>"]
+
+    # Add the <COMPAT>_<UNIT_ADDRESS> style legacy identifier.
+    node.z_primary_ident = node_ident(node)
+
+    # Add z_instances, which are used to create these macros:
+    #
+    # #define DT_INST_<N>_<COMPAT>_<DEFINE> <VAL>
+    inst_idents = []
+    for compat in node.compats:
+        instance_no = node.edt.compat2enabled[compat].index(node)
+        inst_idents.append(f"INST_{instance_no}_{str2ident(compat)}")
+    node.z_inst_idents = inst_idents
+
+    # Add z_aliases, which are used to create these macros:
+    #
+    # #define DT_ALIAS_<ALIAS>_<DEFINE> <VAL>
+    # #define DT_<COMPAT>_<ALIAS>_<DEFINE> <VAL>
+    #
+    # TODO: See if we can remove or deprecate the second form.
+    compat_s = str2ident(node.matching_compat)
+    alias_idents = []
+    for alias in node.aliases:
+        alias_ident = str2ident(alias)
+        alias_idents.append(f"ALIAS_{alias_ident}")
+        # NOTE: in some cases (e.g. PWM_LEDS_BLUE_PWM_LET for
+        # hexiwear_k64) this is a collision with node.z_primary_ident,
+        # making the all_idents checking below necessary.
+        alias_idents.append(f"{compat_s}_{alias_ident}")
+    node.z_alias_idents = alias_idents
+
+    # z_other_idents are all the other identifiers for the node. We
+    # use the term "other" instead of "alias" here because that
+    # overlaps with the node's true aliases in the DTS, which is just
+    # part of what makes up z_other_idents.
+    all_idents = set()
+    all_idents.add(node.z_primary_ident)
+    other_idents = []
+    for ident in node.z_inst_idents + node.z_alias_idents:
+        if ident not in all_idents:
+            other_idents.append(ident)
+            all_idents.add(ident)
+    node.z_other_idents = other_idents
+
+    node.z_idents = [node.z_primary_ident] + node.z_other_idents
+
+
+def for_each_ident(node, function):
+    # Call "function" on node.z_primary_ident, then on each of the
+    # identifiers in node.z_other_idents, in that order.
+
+    function(node, node.z_primary_ident)
+    for ident in node.z_other_idents:
+        function(node, ident)
+
+
 def write_top_comment(edt):
     # Writes an overview comment with misc. info at the top of the header and
     # configuration file