diff --git a/subsys/bluetooth/controller/ll_sw/nordic/hal/nrf5/radio/radio.c b/subsys/bluetooth/controller/ll_sw/nordic/hal/nrf5/radio/radio.c
index f7677eb39c0..d3c12b6106b 100644
--- a/subsys/bluetooth/controller/ll_sw/nordic/hal/nrf5/radio/radio.c
+++ b/subsys/bluetooth/controller/ll_sw/nordic/hal/nrf5/radio/radio.c
@@ -69,7 +69,8 @@ void radio_isr_set(radio_isr_cb_t cb, void *param)
 	isr_cb_param = param;
 	isr_cb = cb;
 
-	nrf_radio_int_enable(0 |
+	nrf_radio_int_enable(NRF_RADIO,
+			     0 |
 				/* RADIO_INTENSET_READY_Msk |
 				 * RADIO_INTENSET_ADDRESS_Msk |
 				 * RADIO_INTENSET_PAYLOAD_Msk |
@@ -108,10 +109,14 @@ void radio_reset(void)
 {
 	irq_disable(RADIO_IRQn);
 
-	nrf_radio_power_set((RADIO_POWER_POWER_Disabled
-			    << RADIO_POWER_POWER_Pos) & RADIO_POWER_POWER_Msk);
-	nrf_radio_power_set((RADIO_POWER_POWER_Enabled << RADIO_POWER_POWER_Pos)
-			    & RADIO_POWER_POWER_Msk);
+	nrf_radio_power_set(
+		NRF_RADIO,
+		(RADIO_POWER_POWER_Disabled << RADIO_POWER_POWER_Pos) &
+			RADIO_POWER_POWER_Msk);
+	nrf_radio_power_set(
+		NRF_RADIO,
+		(RADIO_POWER_POWER_Enabled << RADIO_POWER_POWER_Pos) &
+			RADIO_POWER_POWER_Msk);
 
 	hal_radio_reset();
 
@@ -277,12 +282,12 @@ u32_t radio_rx_chain_delay_get(u8_t phy, u8_t flags)
 
 void radio_rx_enable(void)
 {
-	nrf_radio_task_trigger(NRF_RADIO_TASK_RXEN);
+	nrf_radio_task_trigger(NRF_RADIO, NRF_RADIO_TASK_RXEN);
 }
 
 void radio_tx_enable(void)
 {
-	nrf_radio_task_trigger(NRF_RADIO_TASK_TXEN);
+	nrf_radio_task_trigger(NRF_RADIO, NRF_RADIO_TASK_TXEN);
 }
 
 void radio_disable(void)
@@ -295,7 +300,7 @@ void radio_disable(void)
 #endif /* !CONFIG_BT_CTLR_TIFS_HW */
 
 	NRF_RADIO->SHORTS = 0;
-	nrf_radio_task_trigger(NRF_RADIO_TASK_DISABLE);
+	nrf_radio_task_trigger(NRF_RADIO, NRF_RADIO_TASK_DISABLE);
 }
 
 void radio_status_reset(void)
@@ -473,10 +478,10 @@ static void sw_switch(u8_t dir, u8_t phy_curr, u8_t flags_curr, u8_t phy_next,
 
 	if (delay <
 		SW_SWITCH_TIMER->CC[cc]) {
-		nrf_timer_cc_write(SW_SWITCH_TIMER, cc,
-				   SW_SWITCH_TIMER->CC[cc] - delay);
+		nrf_timer_cc_set(SW_SWITCH_TIMER, cc,
+				 SW_SWITCH_TIMER->CC[cc] - delay);
 	} else {
-		nrf_timer_cc_write(SW_SWITCH_TIMER, cc, 1);
+		nrf_timer_cc_set(SW_SWITCH_TIMER, cc, 1);
 	}
 
 	hal_radio_nrf_ppi_channels_enable(BIT(HAL_SW_SWITCH_TIMER_CLEAR_PPI) |
@@ -592,7 +597,7 @@ u32_t radio_filter_match_get(void)
 
 void radio_bc_configure(u32_t n)
 {
-	nrf_radio_bcc_set(n);
+	nrf_radio_bcc_set(NRF_RADIO, n);
 	NRF_RADIO->SHORTS |= RADIO_SHORTS_ADDRESS_BCSTART_Msk;
 }
 
@@ -634,8 +639,8 @@ void radio_tmr_tifs_set(u32_t tifs)
 #if defined(CONFIG_BT_CTLR_TIFS_HW)
 	NRF_RADIO->TIFS = tifs;
 #else /* !CONFIG_BT_CTLR_TIFS_HW */
-	nrf_timer_cc_write(SW_SWITCH_TIMER,
-			   SW_SWITCH_TIMER_EVTS_COMP(sw_tifs_toggle), tifs);
+	nrf_timer_cc_set(SW_SWITCH_TIMER,
+			 SW_SWITCH_TIMER_EVTS_COMP(sw_tifs_toggle), tifs);
 #endif /* !CONFIG_BT_CTLR_TIFS_HW */
 }
 
@@ -652,7 +657,7 @@ u32_t radio_tmr_start(u8_t trx, u32_t ticks_start, u32_t remainder)
 	EVENT_TIMER->PRESCALER = 4;
 	EVENT_TIMER->BITMODE = 2;	/* 24 - bit */
 
-	nrf_timer_cc_write(EVENT_TIMER, 0, remainder);
+	nrf_timer_cc_set(EVENT_TIMER, 0, remainder);
 
 	nrf_rtc_cc_set(NRF_RTC0, 2, ticks_start);
 	nrf_rtc_event_enable(NRF_RTC0, RTC_EVTENSET_COMPARE2_Msk);
@@ -701,7 +706,7 @@ u32_t radio_tmr_start_tick(u8_t trx, u32_t tick)
 
 	/* Setup compare event with min. 1 us offset */
 	remainder_us = 1;
-	nrf_timer_cc_write(EVENT_TIMER, 0, remainder_us);
+	nrf_timer_cc_set(EVENT_TIMER, 0, remainder_us);
 
 	nrf_rtc_cc_set(NRF_RTC0, 2, tick);
 	nrf_rtc_event_enable(NRF_RTC0, RTC_EVTENSET_COMPARE2_Msk);
@@ -722,7 +727,7 @@ u32_t radio_tmr_start_tick(u8_t trx, u32_t tick)
 
 void radio_tmr_start_us(u8_t trx, u32_t us)
 {
-	nrf_timer_cc_write(EVENT_TIMER, 0, us);
+	nrf_timer_cc_set(EVENT_TIMER, 0, us);
 
 	hal_radio_enable_on_tick_ppi_config_and_enable(trx);
 }
@@ -744,7 +749,7 @@ u32_t radio_tmr_start_now(u8_t trx)
 		start = (now << 1) - start;
 
 		/* Setup compare event with min. 1 us offset */
-		nrf_timer_cc_write(EVENT_TIMER, 0, start + 1);
+		nrf_timer_cc_set(EVENT_TIMER, 0, start + 1);
 
 		/* Capture the current time */
 		nrf_timer_task_trigger(EVENT_TIMER, NRF_TIMER_TASK_CAPTURE1);
@@ -773,7 +778,7 @@ void radio_tmr_stop(void)
 
 void radio_tmr_hcto_configure(u32_t hcto)
 {
-	nrf_timer_cc_write(EVENT_TIMER, 1, hcto);
+	nrf_timer_cc_set(EVENT_TIMER, 1, hcto);
 
 	hal_radio_recv_timeout_cancel_ppi_config();
 	hal_radio_disable_on_hcto_ppi_config();
@@ -933,7 +938,7 @@ void radio_gpio_lna_off(void)
 
 void radio_gpio_pa_lna_enable(u32_t trx_us)
 {
-	nrf_timer_cc_write(EVENT_TIMER, 2, trx_us);
+	nrf_timer_cc_set(EVENT_TIMER, 2, trx_us);
 
 	hal_enable_palna_ppi_config();
 	hal_disable_palna_ppi_config();
diff --git a/subsys/bluetooth/controller/ll_sw/nordic/hal/nrf5/radio/radio_nrf5_ppi.h b/subsys/bluetooth/controller/ll_sw/nordic/hal/nrf5/radio/radio_nrf5_ppi.h
index 98cb0ebc7a6..ebebc748dcf 100644
--- a/subsys/bluetooth/controller/ll_sw/nordic/hal/nrf5/radio/radio_nrf5_ppi.h
+++ b/subsys/bluetooth/controller/ll_sw/nordic/hal/nrf5/radio/radio_nrf5_ppi.h
@@ -11,17 +11,17 @@
 
 static inline void hal_radio_nrf_ppi_channels_enable(u32_t mask)
 {
-	nrf_ppi_channels_enable(mask);
+	nrf_ppi_channels_enable(NRF_PPI, mask);
 }
 
 static inline void hal_radio_nrf_ppi_channels_disable(u32_t mask)
 {
-	nrf_ppi_channels_disable(mask);
+	nrf_ppi_channels_disable(NRF_PPI, mask);
 }
 
 static inline void hal_radio_nrf_ppi_group_disable(u32_t group)
 {
-	nrf_ppi_group_disable(group);
+	nrf_ppi_group_disable(NRF_PPI, group);
 }
 
 /*******************************************************************************
@@ -50,9 +50,11 @@ static inline void hal_radio_enable_on_tick_ppi_config_and_enable(u8_t trx)
 	 * Just enable and disable them accordingly.
 	 */
 	nrf_ppi_channels_disable(
+		NRF_PPI,
 		trx ? BIT(HAL_RADIO_ENABLE_RX_ON_TICK_PPI)
 		    : BIT(HAL_RADIO_ENABLE_TX_ON_TICK_PPI));
 	nrf_ppi_channels_enable(
+		NRF_PPI,
 		trx ? BIT(HAL_RADIO_ENABLE_TX_ON_TICK_PPI)
 		    : BIT(HAL_RADIO_ENABLE_RX_ON_TICK_PPI));
 }
@@ -68,10 +70,11 @@ static inline void hal_radio_enable_on_tick_ppi_config_and_enable(u8_t trx)
 	u32_t event_address = (trx ? (u32_t)&(NRF_RADIO->TASKS_TXEN)
 				   : (u32_t)&(NRF_RADIO->TASKS_RXEN));
 	nrf_ppi_channel_endpoint_setup(
+		NRF_PPI,
 		HAL_RADIO_ENABLE_ON_TICK_PPI,
 		(u32_t)&(EVENT_TIMER->EVENTS_COMPARE[0]),
 		event_address);
-	nrf_ppi_channels_enable(BIT(HAL_RADIO_ENABLE_ON_TICK_PPI));
+	nrf_ppi_channels_enable(NRF_PPI, BIT(HAL_RADIO_ENABLE_ON_TICK_PPI));
 }
 
 #endif /* (EVENT_TIMER_ID == 0) */
@@ -104,6 +107,7 @@ static inline void hal_radio_recv_timeout_cancel_ppi_config(void)
 static inline void hal_radio_recv_timeout_cancel_ppi_config(void)
 {
 	nrf_ppi_channel_endpoint_setup(
+		NRF_PPI,
 		HAL_RADIO_RECV_TIMEOUT_CANCEL_PPI,
 		(u32_t)&(NRF_RADIO->EVENTS_ADDRESS),
 		(u32_t)&(EVENT_TIMER->TASKS_CAPTURE[1]));
@@ -139,6 +143,7 @@ static inline void hal_radio_disable_on_hcto_ppi_config(void)
 static inline void hal_radio_disable_on_hcto_ppi_config(void)
 {
 	nrf_ppi_channel_endpoint_setup(
+		NRF_PPI,
 		HAL_RADIO_DISABLE_ON_HCTO_PPI,
 		(u32_t)&(EVENT_TIMER->EVENTS_COMPARE[1]),
 		(u32_t)&(NRF_RADIO->TASKS_DISABLE));
@@ -174,6 +179,7 @@ static inline void hal_radio_end_time_capture_ppi_config(void)
 static inline void hal_radio_end_time_capture_ppi_config(void)
 {
 	nrf_ppi_channel_endpoint_setup(
+		NRF_PPI,
 		HAL_RADIO_END_TIME_CAPTURE_PPI,
 		(u32_t)&(NRF_RADIO->EVENTS_END),
 		(u32_t)&(EVENT_TIMER->TASKS_CAPTURE[2]));
@@ -190,6 +196,7 @@ static inline void hal_radio_end_time_capture_ppi_config(void)
 static inline void hal_event_timer_start_ppi_config(void)
 {
 	nrf_ppi_channel_endpoint_setup(
+		NRF_PPI,
 		HAL_EVENT_TIMER_START_PPI,
 		(u32_t)&(NRF_RTC0->EVENTS_COMPARE[2]),
 		(u32_t)&(EVENT_TIMER->TASKS_START));
@@ -205,6 +212,7 @@ static inline void hal_event_timer_start_ppi_config(void)
 static inline void hal_radio_ready_time_capture_ppi_config(void)
 {
 	nrf_ppi_channel_endpoint_setup(
+		NRF_PPI,
 		HAL_RADIO_READY_TIME_CAPTURE_PPI,
 		(u32_t)&(NRF_RADIO->EVENTS_READY),
 		(u32_t)&(EVENT_TIMER->TASKS_CAPTURE[0]));
@@ -250,6 +258,7 @@ static inline void hal_trigger_aar_ppi_config(void)
 static inline void hal_trigger_rateoverride_ppi_config(void)
 {
 	nrf_ppi_channel_endpoint_setup(
+		NRF_PPI,
 		HAL_TRIGGER_RATEOVERRIDE_PPI,
 		(u32_t)&(NRF_RADIO->EVENTS_RATEBOOST),
 		(u32_t)&(NRF_CCM->TASKS_RATEOVERRIDE));
@@ -265,6 +274,7 @@ static inline void hal_trigger_rateoverride_ppi_config(void)
 static inline void hal_enable_palna_ppi_config(void)
 {
 	nrf_ppi_channel_endpoint_setup(
+		NRF_PPI,
 		HAL_ENABLE_PALNA_PPI,
 		(u32_t)&(EVENT_TIMER->EVENTS_COMPARE[2]),
 		(u32_t)&(NRF_GPIOTE->TASKS_OUT[
@@ -275,7 +285,9 @@ static inline void hal_enable_palna_ppi_config(void)
 
 static inline void hal_disable_palna_ppi_config(void)
 {
-	nrf_ppi_channel_endpoint_setup(HAL_DISABLE_PALNA_PPI,
+	nrf_ppi_channel_endpoint_setup(
+		NRF_PPI,
+		HAL_DISABLE_PALNA_PPI,
 		(u32_t)&(NRF_RADIO->EVENTS_DISABLED),
 		(u32_t)&(NRF_GPIOTE->TASKS_OUT[
 				CONFIG_BT_CTLR_PA_LNA_GPIOTE_CHAN]));
@@ -299,6 +311,7 @@ static inline void hal_disable_palna_ppi_config(void)
 static inline void hal_sw_switch_timer_clear_ppi_config(void)
 {
 	nrf_ppi_channel_endpoint_setup(
+		NRF_PPI,
 		HAL_SW_SWITCH_TIMER_CLEAR_PPI,
 		(u32_t)&(NRF_RADIO->EVENTS_END),
 		(u32_t)&(SW_SWITCH_TIMER->TASKS_CLEAR));
@@ -318,6 +331,7 @@ static inline void hal_sw_switch_timer_clear_ppi_config(void)
 static inline void hal_sw_switch_timer_clear_ppi_config(void)
 {
 	nrf_ppi_fork_endpoint_setup(
+		NRF_PPI,
 		HAL_RADIO_END_TIME_CAPTURE_PPI,
 		(u32_t)&(SW_SWITCH_TIMER->TASKS_CLEAR));
 }
@@ -408,7 +422,9 @@ static inline void hal_radio_sw_switch_setup(
 	/* Wire RADIO END event to PPI Group[<index>] enable task,
 	 * over PPI[<HAL_SW_SWITCH_GROUP_TASK_ENABLE_PPI>]
 	 */
-	nrf_ppi_channel_endpoint_setup(HAL_SW_SWITCH_GROUP_TASK_ENABLE_PPI,
+	nrf_ppi_channel_endpoint_setup(
+		NRF_PPI,
+		HAL_SW_SWITCH_GROUP_TASK_ENABLE_PPI,
 		HAL_SW_SWITCH_GROUP_TASK_ENABLE_PPI_EVT,
 		HAL_SW_SWITCH_GROUP_TASK_ENABLE_PPI_TASK(ppi_group_index));
 
@@ -418,19 +434,25 @@ static inline void hal_radio_sw_switch_setup(
 	 * the function depending on the desired direction
 	 * (TX/RX).
 	 */
-	nrf_ppi_event_endpoint_setup(radio_enable_ppi,
+	nrf_ppi_event_endpoint_setup(
+		NRF_PPI,
+		radio_enable_ppi,
 		HAL_SW_SWITCH_RADIO_ENABLE_PPI_EVT(compare_reg));
 }
 
 static inline void hal_radio_txen_on_sw_switch(u8_t ppi)
 {
-	nrf_ppi_task_endpoint_setup(ppi,
+	nrf_ppi_task_endpoint_setup(
+		NRF_PPI,
+		ppi,
 		HAL_SW_SWITCH_RADIO_ENABLE_PPI_TASK_TX);
 }
 
 static inline void hal_radio_rxen_on_sw_switch(u8_t ppi)
 {
-	nrf_ppi_task_endpoint_setup(ppi,
+	nrf_ppi_task_endpoint_setup(
+		NRF_PPI,
+		ppi,
 		HAL_SW_SWITCH_RADIO_ENABLE_PPI_TASK_RX);
 }
 
@@ -440,8 +462,10 @@ static inline void hal_radio_sw_switch_disable(void)
 	 * - Clearing SW SWITCH TIMER on RADIO END event
 	 * - Enabling SW SWITCH PPI Group on RADIO END event
 	 */
-	nrf_ppi_channels_disable(BIT(HAL_SW_SWITCH_TIMER_CLEAR_PPI) |
-		 BIT(HAL_SW_SWITCH_GROUP_TASK_ENABLE_PPI));
+	nrf_ppi_channels_disable(
+		NRF_PPI,
+		BIT(HAL_SW_SWITCH_TIMER_CLEAR_PPI) |
+		BIT(HAL_SW_SWITCH_GROUP_TASK_ENABLE_PPI));
 }
 
 #if defined(CONFIG_BT_CTLR_PHY_CODED) && \
@@ -512,6 +536,7 @@ static inline void hal_radio_sw_switch_coded_tx_config_set(u8_t ppi_en,
 			group_index);
 
 	nrf_ppi_channels_enable(
+		NRF_PPI,
 		BIT(HAL_SW_SWITCH_TIMER_S8_DISABLE_PPI));
 }
 
@@ -542,6 +567,7 @@ static inline void hal_radio_group_task_disable_ppi_setup(void)
 	 * PPI Group TASK [<index-0>] DISABLE task, over PPI<index-0>.
 	 */
 	nrf_ppi_channel_endpoint_setup(
+		NRF_PPI,
 		HAL_SW_SWITCH_GROUP_TASK_DISABLE_PPI(0),
 		HAL_SW_SWITCH_GROUP_TASK_DISABLE_PPI_EVT(
 			SW_SWITCH_TIMER_EVTS_COMP(0)),
@@ -551,6 +577,7 @@ static inline void hal_radio_group_task_disable_ppi_setup(void)
 	 * PPI Group[<index-1>] Disable Task, over PPI<index-1>.
 	 */
 	nrf_ppi_channel_endpoint_setup(
+		NRF_PPI,
 		HAL_SW_SWITCH_GROUP_TASK_DISABLE_PPI(1),
 		HAL_SW_SWITCH_GROUP_TASK_DISABLE_PPI_EVT(
 			SW_SWITCH_TIMER_EVTS_COMP(1)),