diff --git a/tests/drivers/uart/uart_async_api/boards/nucleo_l4r5zi.overlay b/tests/drivers/uart/uart_async_api/boards/nucleo_l4r5zi.overlay
new file mode 100644
index 00000000000..3b375402094
--- /dev/null
+++ b/tests/drivers/uart/uart_async_api/boards/nucleo_l4r5zi.overlay
@@ -0,0 +1,15 @@
+/* SPDX-License-Identifier: Apache-2.0 */
+
+&usart3 {
+	dmas = <&dmamux1 5 29 0x440 0>,
+		<&dmamux1 4 28 0x480 0>;
+	dma-names = "tx", "rx";
+};
+
+&dma1 {
+	status = "okay";
+};
+
+&dmamux1 {
+	status = "okay";
+};
diff --git a/tests/drivers/uart/uart_async_api/src/test_uart.h b/tests/drivers/uart/uart_async_api/src/test_uart.h
index 7df4d9cd379..953a4d4a206 100644
--- a/tests/drivers/uart/uart_async_api/src/test_uart.h
+++ b/tests/drivers/uart/uart_async_api/src/test_uart.h
@@ -29,6 +29,8 @@
 #define UART_DEVICE_NAME DT_LABEL(DT_NODELABEL(sercom3))
 #elif defined(CONFIG_BOARD_ATSAME54_XPRO)
 #define UART_DEVICE_NAME DT_LABEL(DT_NODELABEL(sercom1))
+#elif defined(CONFIG_BOARD_NUCLEO_L4R5ZI)
+#define UART_DEVICE_NAME DT_LABEL(DT_NODELABEL(usart3))
 #else
 #define UART_DEVICE_NAME CONFIG_UART_CONSOLE_ON_DEV_NAME
 #endif