diff --git a/modules/mbedtls/configs/config-coap.h b/modules/mbedtls/configs/config-coap.h
index 18ed60ef7c7..f610eb20bc6 100644
--- a/modules/mbedtls/configs/config-coap.h
+++ b/modules/mbedtls/configs/config-coap.h
@@ -35,6 +35,7 @@
 #define MBEDTLS_PLATFORM_C
 #define MBEDTLS_PLATFORM_MEMORY
 #define MBEDTLS_MEMORY_BUFFER_ALLOC_C
+#define MBEDTLS_MEMORY_ALIGN_MULTIPLE (sizeof(void *))
 #define MBEDTLS_PLATFORM_NO_STD_FUNCTIONS
 #define MBEDTLS_PLATFORM_EXIT_ALT
 #define MBEDTLS_NO_PLATFORM_ENTROPY
diff --git a/modules/mbedtls/configs/config-mini-dtls1_2.h b/modules/mbedtls/configs/config-mini-dtls1_2.h
index 3a13e0d7ca7..ee0d70b5915 100644
--- a/modules/mbedtls/configs/config-mini-dtls1_2.h
+++ b/modules/mbedtls/configs/config-mini-dtls1_2.h
@@ -16,6 +16,7 @@
 #define MBEDTLS_PLATFORM_C
 #define MBEDTLS_PLATFORM_MEMORY
 #define MBEDTLS_MEMORY_BUFFER_ALLOC_C
+#define MBEDTLS_MEMORY_ALIGN_MULTIPLE (sizeof(void *))
 #define MBEDTLS_PLATFORM_NO_STD_FUNCTIONS
 #define MBEDTLS_PLATFORM_EXIT_ALT
 #define MBEDTLS_NO_PLATFORM_ENTROPY
diff --git a/modules/mbedtls/configs/config-mini-tls1_2.h b/modules/mbedtls/configs/config-mini-tls1_2.h
index f725801a62e..4045fe70478 100644
--- a/modules/mbedtls/configs/config-mini-tls1_2.h
+++ b/modules/mbedtls/configs/config-mini-tls1_2.h
@@ -15,6 +15,7 @@
 #define MBEDTLS_PLATFORM_C
 #define MBEDTLS_PLATFORM_MEMORY
 #define MBEDTLS_MEMORY_BUFFER_ALLOC_C
+#define MBEDTLS_MEMORY_ALIGN_MULTIPLE (sizeof(void *))
 #define MBEDTLS_PLATFORM_NO_STD_FUNCTIONS
 #define MBEDTLS_PLATFORM_EXIT_ALT
 #define MBEDTLS_NO_PLATFORM_ENTROPY
diff --git a/modules/mbedtls/configs/config-threadnet.h b/modules/mbedtls/configs/config-threadnet.h
index 6804c790fbf..c6676f03433 100644
--- a/modules/mbedtls/configs/config-threadnet.h
+++ b/modules/mbedtls/configs/config-threadnet.h
@@ -38,6 +38,7 @@
 #define MBEDTLS_PLATFORM_C
 #define MBEDTLS_PLATFORM_MEMORY
 #define MBEDTLS_MEMORY_BUFFER_ALLOC_C
+#define MBEDTLS_MEMORY_ALIGN_MULTIPLE (sizeof(void *))
 #define MBEDTLS_PLATFORM_NO_STD_FUNCTIONS
 #define MBEDTLS_PLATFORM_EXIT_ALT
 #define MBEDTLS_NO_PLATFORM_ENTROPY
diff --git a/modules/mbedtls/configs/config-tls-generic.h b/modules/mbedtls/configs/config-tls-generic.h
index 2268571abe0..9d5dcfdaa47 100644
--- a/modules/mbedtls/configs/config-tls-generic.h
+++ b/modules/mbedtls/configs/config-tls-generic.h
@@ -15,6 +15,7 @@
 #define MBEDTLS_PLATFORM_C
 #define MBEDTLS_PLATFORM_MEMORY
 #define MBEDTLS_MEMORY_BUFFER_ALLOC_C
+#define MBEDTLS_MEMORY_ALIGN_MULTIPLE (sizeof(void *))
 #define MBEDTLS_PLATFORM_EXIT_ALT
 #define MBEDTLS_NO_PLATFORM_ENTROPY