diff --git a/boards/arm/stm32l562e_dk/doc/index.rst b/boards/arm/stm32l562e_dk/doc/index.rst
index 80b26c73265..9d48980f4d0 100644
--- a/boards/arm/stm32l562e_dk/doc/index.rst
+++ b/boards/arm/stm32l562e_dk/doc/index.rst
@@ -185,6 +185,8 @@ hardware features:
 +-----------+------------+-------------------------------------+
 | WATCHDOG  | on-chip    | independent watchdog                |
 +-----------+------------+-------------------------------------+
+| USB       | on-chip    | usb                                 |
++-----------+------------+-------------------------------------+
 
 Other hardware features are not yet supported on this Zephyr port.
 
diff --git a/boards/arm/stm32l562e_dk/stm32l562e_dk.yaml b/boards/arm/stm32l562e_dk/stm32l562e_dk.yaml
index e14807056b6..16462654f6b 100644
--- a/boards/arm/stm32l562e_dk/stm32l562e_dk.yaml
+++ b/boards/arm/stm32l562e_dk/stm32l562e_dk.yaml
@@ -18,5 +18,6 @@ supported:
   - dma
   - usart
   - arduino_spi
+  - usb
 ram: 192
 flash: 512
diff --git a/boards/arm/stm32l562e_dk/stm32l562e_dk_common.dtsi b/boards/arm/stm32l562e_dk/stm32l562e_dk_common.dtsi
index a785e6991c5..d724ba4f851 100644
--- a/boards/arm/stm32l562e_dk/stm32l562e_dk_common.dtsi
+++ b/boards/arm/stm32l562e_dk/stm32l562e_dk_common.dtsi
@@ -146,3 +146,8 @@
 	cs-gpios = <&gpioe 0 (GPIO_ACTIVE_LOW | GPIO_PULL_UP)>;
 	status = "okay";
 };
+
+zephyr_udc0: &usb {
+	pinctrl-0 = <&usb_dp_pa12 &usb_dm_pa11>;
+	status = "okay";
+};
diff --git a/dts/arm/st/l5/stm32l5.dtsi b/dts/arm/st/l5/stm32l5.dtsi
index 5d554d8d669..6ff4473ce70 100644
--- a/dts/arm/st/l5/stm32l5.dtsi
+++ b/dts/arm/st/l5/stm32l5.dtsi
@@ -564,6 +564,26 @@
 			label = "ADC_2";
 			#io-channel-cells = <1>;
 		};
+
+		usb: usb@4000d400 {
+			compatible = "st,stm32-usb";
+			reg = <0x4000d400 0x400>;
+			interrupts = <73 0>;
+			interrupt-names = "usb";
+			num-bidir-endpoints = <8>;
+			ram-size = <1024>;
+			status = "disabled";
+			clocks = <&rcc STM32_CLOCK_BUS_APB1_2 0x00200000>;
+			phys = <&usb_fs_phy>;
+			label = "USB";
+		};
+
+	};
+
+	usb_fs_phy: usbphy {
+		compatible = "usb-nop-xceiv";
+		#phy-cells = <0>;
+		label = "USB_FS_PHY";
 	};
 };