diff --git a/modules/hal_nordic/nrfx/Kconfig b/modules/hal_nordic/nrfx/Kconfig
index 53a77e60175..5dcda73c9be 100644
--- a/modules/hal_nordic/nrfx/Kconfig
+++ b/modules/hal_nordic/nrfx/Kconfig
@@ -82,6 +82,11 @@ config NRFX_I2S0
 	depends on $(dt_nodelabel_has_compat,i2s0,$(DT_COMPAT_NORDIC_NRF_I2S))
 	select NRFX_I2S
 
+config NRFX_I2S20
+	bool "I2S20 driver instance"
+	depends on $(dt_nodelabel_has_compat,i2s20,$(DT_COMPAT_NORDIC_NRF_I2S))
+	select NRFX_I2S
+
 config NRFX_IPC
 	bool "IPC driver"
 	depends on $(dt_has_compat,$(DT_COMPAT_NORDIC_NRF_IPC))
diff --git a/modules/hal_nordic/nrfx/nrfx_config.h b/modules/hal_nordic/nrfx/nrfx_config.h
index f799c4207d5..aaf31751004 100644
--- a/modules/hal_nordic/nrfx/nrfx_config.h
+++ b/modules/hal_nordic/nrfx/nrfx_config.h
@@ -141,6 +141,9 @@
 #ifdef CONFIG_NRFX_I2S0
 #define NRFX_I2S0_ENABLED 1
 #endif
+#ifdef CONFIG_NRFX_I2S20
+#define NRFX_I2S20_ENABLED 1
+#endif
 
 #ifdef CONFIG_NRFX_IPC
 #define NRFX_IPC_ENABLED 1