diff --git a/samples/modules/canopennode/CMakeLists.txt b/samples/modules/canopennode/CMakeLists.txt
index fb792ec299a..dea27437d2e 100644
--- a/samples/modules/canopennode/CMakeLists.txt
+++ b/samples/modules/canopennode/CMakeLists.txt
@@ -4,9 +4,6 @@ cmake_minimum_required(VERSION 3.20.0)
 
 macro(app_set_runner_args)
   board_runner_args(canopen "--node-id=${CONFIG_CANOPEN_NODE_ID}")
-  board_runner_args(dfu-util "--dfuse-modifiers=force:mass-erase")
-  board_runner_args(pyocd "--erase")
-  board_runner_args(nrfjprog "--erase")
 endmacro()
 
 find_package(Zephyr REQUIRED HINTS $ENV{ZEPHYR_BASE})
diff --git a/samples/modules/canopennode/README.rst b/samples/modules/canopennode/README.rst
index fcd8649b690..66fc6514369 100644
--- a/samples/modules/canopennode/README.rst
+++ b/samples/modules/canopennode/README.rst
@@ -394,48 +394,33 @@ Building and Running for FRDM-K64F
 The sample can be rebuilt with MCUboot and program download support
 for the FRDM-K64F as follows:
 
-#. Build and flash MCUboot by following the instructions in the
-   :ref:`mcuboot` documentation page.
-
-#. Rebuild the CANopen sample with MCUboot support:
+#. Build the CANopenNode sample with MCUboot support:
 
    .. zephyr-app-commands::
-      :zephyr-app: samples/modules/canopennode
+      :tool: west
+      :app: samples/modules/canopennode
       :board: frdm_k64f
       :goals: build
-      :gen-args: -DCONFIG_BOOTLOADER_MCUBOOT=y
+      :west-args: --sysbuild
       :compact:
 
-#. Sign the newly rebuilt CANopen sample binary (using either the
-   demonstration-only RSA key from MCUboot or any other key used when
-   building MCUboot itself):
+#. Flash the newly built MCUboot and CANopen sample binaries using west:
 
    .. code-block:: console
 
-      west sign -t imgtool --bin --no-hex -- --key mcuboot/root-rsa-2048.pem \
-              --version 1.0.0
-
-#. Flash the newly signed CANopen sample binary using west:
-
-   .. code-block:: console
-
-      west flash --skip-rebuild --bin-file zephyr/zephyr.signed.bin
+      west flash --skip-rebuild
 
 #. Confirm the newly flashed firmware image using west:
 
    .. code-block:: console
 
-      west flash --skip-rebuild --runner canopen --confirm-only
+      west flash --skip-rebuild --domain canopennode --runner canopen --confirm-only
 
-#. Finally, resign the CANopen sample binary with a new version number
-   and perform a program download over CANopen:
+#. Finally, perform a program download via CANopen:
 
    .. code-block:: console
 
-      west sign -t imgtool --bin --no-hex  -- --key mcuboot/root-rsa-2048.pem \
-              --version 1.0.1
-      west flash --skip-rebuild --bin-file zephyr/zephyr.signed.bin \
-              --runner canopen
+      west flash --skip-rebuild --domain canopennode --runner canopen
 
 Modifying the Object Dictionary
 *******************************
diff --git a/samples/modules/canopennode/sample.yaml b/samples/modules/canopennode/sample.yaml
index 43877bd8289..e1448bf73d4 100644
--- a/samples/modules/canopennode/sample.yaml
+++ b/samples/modules/canopennode/sample.yaml
@@ -18,14 +18,9 @@ tests:
             CONFIG_FLASH_HAS_DRIVER_ENABLED
     platform_exclude: nucleo_h723zg nucleo_h743zi nucleo_h745zi_q nucleo_h753zi
   sample.modules.canopennode.program_download:
-    build_only: true
-    platform_exclude: native_posix native_posix_64 rcar_h3ulcb_cr7 qemu_x86 qemu_x86_64
-    filter: dt_label_with_parent_compat_enabled("slot0_partition", "fixed-partitions") and
-            dt_label_with_parent_compat_enabled("slot1_partition", "fixed-partitions") and
-            dt_label_with_parent_compat_enabled("storage_partition", "fixed-partitions") and
-            dt_chosen_enabled("zephyr,flash-controller") and
-            CONFIG_FLASH_HAS_DRIVER_ENABLED
-    extra_configs:
-      - CONFIG_BOOTLOADER_MCUBOOT=y
+    sysbuild: True
+    platform_allow: frdm_k64f twr_ke18f
+    integration_platforms:
+      - frdm_k64f
   sample.modules.canopennode.no_storage:
     extra_args: CONF_FILE=prj_no_storage.conf
diff --git a/samples/modules/canopennode/sysbuild.conf b/samples/modules/canopennode/sysbuild.conf
new file mode 100644
index 00000000000..47f00ff3cff
--- /dev/null
+++ b/samples/modules/canopennode/sysbuild.conf
@@ -0,0 +1 @@
+SB_CONFIG_BOOTLOADER_MCUBOOT=y