diff --git a/drivers/serial/uart_mcux_lpuart.c b/drivers/serial/uart_mcux_lpuart.c
index 5bc8f126712..e434860a264 100644
--- a/drivers/serial/uart_mcux_lpuart.c
+++ b/drivers/serial/uart_mcux_lpuart.c
@@ -1152,7 +1152,8 @@ static const struct uart_driver_api mcux_lpuart_driver_api = {
 #define MCUX_LPUART_IRQ_DEFINE(n)						\
 	static void mcux_lpuart_config_func_##n(const struct device *dev)	\
 	{									\
-		MCUX_LPUART_IRQ_INSTALL(n, 0);				\
+		IF_ENABLED(DT_INST_IRQ_HAS_IDX(n, 0),			\
+			   (MCUX_LPUART_IRQ_INSTALL(n, 0);))		\
 									\
 		IF_ENABLED(DT_INST_IRQ_HAS_IDX(n, 1),			\
 			   (MCUX_LPUART_IRQ_INSTALL(n, 1);))		\
diff --git a/dts/bindings/serial/nxp,kinetis-lpuart.yaml b/dts/bindings/serial/nxp,kinetis-lpuart.yaml
index 8fbf2f2bd22..1b8f5400722 100644
--- a/dts/bindings/serial/nxp,kinetis-lpuart.yaml
+++ b/dts/bindings/serial/nxp,kinetis-lpuart.yaml
@@ -8,9 +8,6 @@ properties:
   reg:
     required: true
 
-  interrupts:
-    required: true
-
   nxp,loopback:
     type: boolean
     description: |