diff --git a/boards/arm/mimxrt595_evk/mimxrt595_evk_cm33.dts b/boards/arm/mimxrt595_evk/mimxrt595_evk_cm33.dts
index 4a373e72864..25b6c605037 100644
--- a/boards/arm/mimxrt595_evk/mimxrt595_evk_cm33.dts
+++ b/boards/arm/mimxrt595_evk/mimxrt595_evk_cm33.dts
@@ -539,3 +539,8 @@ zephyr_udc0: &usbhs {
 
 	status = "okay";
 };
+
+/* Disable this node if not using USB and need another MPU region */
+&sram1 {
+	status = "okay";
+};
diff --git a/boards/arm/mimxrt685_evk/mimxrt685_evk_cm33.dts b/boards/arm/mimxrt685_evk/mimxrt685_evk_cm33.dts
index 8907ac02e48..6c36982d91f 100644
--- a/boards/arm/mimxrt685_evk/mimxrt685_evk_cm33.dts
+++ b/boards/arm/mimxrt685_evk/mimxrt685_evk_cm33.dts
@@ -403,3 +403,8 @@ zephyr_udc0: &usbhs {
 
 	status = "okay";
 };
+
+/* Disable this node if not using USB and need another MPU region */
+&sram1 {
+	status = "okay";
+};