diff --git a/subsys/bluetooth/controller/ll_sw/isoal.c b/subsys/bluetooth/controller/ll_sw/isoal.c
index e5859959697..d0c5b1a75d3 100644
--- a/subsys/bluetooth/controller/ll_sw/isoal.c
+++ b/subsys/bluetooth/controller/ll_sw/isoal.c
@@ -71,7 +71,7 @@ LOG_MODULE_REGISTER(bt_ctlr_isoal, CONFIG_BT_CTLR_ISOAL_LOG_LEVEL);
 /* Defined the wrapping point and mid point in the range of time input values,
  * which depend on range of the controller's clock in microseconds.
  */
-#define ISOAL_TIME_WRAPPING_POINT_US      (HAL_TICKER_TICKS_TO_US(HAL_TICKER_CNTR_MASK))
+#define ISOAL_TIME_WRAPPING_POINT_US      (HAL_TICKER_TICKS_TO_US_64BIT(HAL_TICKER_CNTR_MASK))
 #define ISOAL_TIME_MID_POINT_US           (ISOAL_TIME_WRAPPING_POINT_US / 2)
 #define ISOAL_TIME_SPAN_FULL_US           (ISOAL_TIME_WRAPPING_POINT_US + 1)
 #define ISOAL_TIME_SPAN_HALF_US           (ISOAL_TIME_SPAN_FULL_US / 2)
diff --git a/subsys/bluetooth/controller/ll_sw/nordic/hal/nrf5/ticker.h b/subsys/bluetooth/controller/ll_sw/nordic/hal/nrf5/ticker.h
index 1a5c1a3f8a7..0def788727b 100644
--- a/subsys/bluetooth/controller/ll_sw/nordic/hal/nrf5/ticker.h
+++ b/subsys/bluetooth/controller/ll_sw/nordic/hal/nrf5/ticker.h
@@ -44,12 +44,14 @@
 	)
 
 /* Macro to translate tick units to microseconds. */
-#define HAL_TICKER_TICKS_TO_US(x) \
+#define HAL_TICKER_TICKS_TO_US_64BIT(x) \
 	( \
-		((uint32_t)(((uint64_t)(x) * HAL_TICKER_CNTR_CLK_UNIT_FSEC) / \
-		 HAL_TICKER_FSEC_PER_USEC)) \
+		(((uint64_t)(x) * HAL_TICKER_CNTR_CLK_UNIT_FSEC) / \
+		 HAL_TICKER_FSEC_PER_USEC) \
 	)
 
+#define HAL_TICKER_TICKS_TO_US(x) ((uint32_t)HAL_TICKER_TICKS_TO_US_64BIT(x))
+
 /* Macro returning remainder in picoseconds (to fit in 32-bits) */
 #define HAL_TICKER_REMAINDER(x) \
 	( \
diff --git a/subsys/bluetooth/controller/ll_sw/nordic/lll/lll_central_iso.c b/subsys/bluetooth/controller/ll_sw/nordic/lll/lll_central_iso.c
index 1a4d09c47c6..9d8b517cb55 100644
--- a/subsys/bluetooth/controller/ll_sw/nordic/lll/lll_central_iso.c
+++ b/subsys/bluetooth/controller/ll_sw/nordic/lll/lll_central_iso.c
@@ -775,7 +775,7 @@ static void isr_rx(void *param)
 						(cis_lll->rx.payload_count / cis_lll->rx.bn)) *
 					       cig_lll->iso_interval_us;
 			iso_meta->timestamp %=
-				HAL_TICKER_TICKS_TO_US(BIT(HAL_TICKER_CNTR_MSBIT + 1U));
+				HAL_TICKER_TICKS_TO_US_64BIT(BIT64(HAL_TICKER_CNTR_MSBIT + 1U));
 			iso_meta->status = 0U;
 
 			ull_iso_pdu_rx_alloc();
diff --git a/subsys/bluetooth/controller/ll_sw/nordic/lll/lll_peripheral_iso.c b/subsys/bluetooth/controller/ll_sw/nordic/lll/lll_peripheral_iso.c
index 07b6c5aae09..4c57de3e065 100644
--- a/subsys/bluetooth/controller/ll_sw/nordic/lll/lll_peripheral_iso.c
+++ b/subsys/bluetooth/controller/ll_sw/nordic/lll/lll_peripheral_iso.c
@@ -606,7 +606,7 @@ static void isr_rx(void *param)
 						(cis_lll->rx.payload_count / cis_lll->rx.bn)) *
 					       cig_lll->iso_interval_us;
 			iso_meta->timestamp %=
-				HAL_TICKER_TICKS_TO_US(BIT(HAL_TICKER_CNTR_MSBIT + 1U));
+				HAL_TICKER_TICKS_TO_US_64BIT(BIT64(HAL_TICKER_CNTR_MSBIT + 1U));
 			iso_meta->status = 0U;
 
 			ull_iso_pdu_rx_alloc();
diff --git a/subsys/bluetooth/controller/ll_sw/nordic/lll/lll_sync_iso.c b/subsys/bluetooth/controller/ll_sw/nordic/lll/lll_sync_iso.c
index 14de5add323..42c57790516 100644
--- a/subsys/bluetooth/controller/ll_sw/nordic/lll/lll_sync_iso.c
+++ b/subsys/bluetooth/controller/ll_sw/nordic/lll/lll_sync_iso.c
@@ -1366,7 +1366,7 @@ static void isr_rx_iso_data_valid(const struct lll_sync_iso *const lll,
 			       lll->sub_interval * ((lll->irc * lll->bn) +
 						    lll->ptc));
 	iso_meta->timestamp %=
-		HAL_TICKER_TICKS_TO_US(BIT(HAL_TICKER_CNTR_MSBIT + 1U));
+		HAL_TICKER_TICKS_TO_US_64BIT(BIT64(HAL_TICKER_CNTR_MSBIT + 1U));
 	iso_meta->status = 0U;
 }
 
@@ -1390,7 +1390,7 @@ static void isr_rx_iso_data_invalid(const struct lll_sync_iso *const lll,
 			       lll->sub_interval * ((lll->irc * lll->bn) +
 						    lll->ptc));
 	iso_meta->timestamp %=
-		HAL_TICKER_TICKS_TO_US(BIT(HAL_TICKER_CNTR_MSBIT + 1U));
+		HAL_TICKER_TICKS_TO_US_64BIT(BIT64(HAL_TICKER_CNTR_MSBIT + 1U));
 	iso_meta->status = 1U;
 }
 
diff --git a/tests/bluetooth/ctrl_isoal/src/sub_sets/isoal_test_rx.c b/tests/bluetooth/ctrl_isoal/src/sub_sets/isoal_test_rx.c
index b7beb40f38a..1422d56ee3a 100644
--- a/tests/bluetooth/ctrl_isoal/src/sub_sets/isoal_test_rx.c
+++ b/tests/bluetooth/ctrl_isoal/src/sub_sets/isoal_test_rx.c
@@ -925,14 +925,18 @@ ZTEST(test_rx_unframed, test_rx_time_wrapping)
 
 	/* Maximum negative difference from 0 */
 	time_now = 0;
-	time_diff = (time_wrapping_point == UINT32_MAX ? INT32_MIN : -ISOAL_TIME_WRAPPING_POINT_US);
+	time_diff = (time_wrapping_point == UINT32_MAX) ?
+		    INT32_MIN :
+		    -((int64_t)ISOAL_TIME_WRAPPING_POINT_US);
 	expected_result = ISOAL_TIME_WRAPPING_POINT_US + time_diff + 1;
 	result = isoal_get_wrapped_time_test(time_now, time_diff);
 	zassert_equal(result, expected_result, "%lu != %lu", result, expected_result);
 
 	/* Maximum negative difference from maximum time */
 	time_now = ISOAL_TIME_WRAPPING_POINT_US;
-	time_diff = (time_wrapping_point == UINT32_MAX ? INT32_MIN : -ISOAL_TIME_WRAPPING_POINT_US);
+	time_diff = (time_wrapping_point == UINT32_MAX) ?
+		    INT32_MIN :
+		    -((int64_t)ISOAL_TIME_WRAPPING_POINT_US);
 	expected_result = ISOAL_TIME_WRAPPING_POINT_US + time_diff;
 	result = isoal_get_wrapped_time_test(time_now, time_diff);
 	zassert_equal(result, expected_result, "%lu != %lu", result, expected_result);