diff --git a/subsys/bluetooth/controller/Kconfig b/subsys/bluetooth/controller/Kconfig
index 9e1438db9b1..17bbf46b417 100644
--- a/subsys/bluetooth/controller/Kconfig
+++ b/subsys/bluetooth/controller/Kconfig
@@ -38,6 +38,8 @@ config BLUETOOTH_CONTROLLER_RX_STACK_SIZE
 	  which all radio messages are encoded into HCI events or data
 	  before passing it to Bluetooth receiving thread.
 
+comment "BLE Controller debug configuration"
+
 config BLUETOOTH_CONTROLLER_ASSERT_HANDLER
 	bool "Bluetooth Controller Assertion Handler"
 	depends on BLUETOOTH_HCI_RAW
@@ -48,5 +50,12 @@ config BLUETOOTH_CONTROLLER_ASSERT_HANDLER
 	  and will be invoked whenever the controller code encounters
 	  an unrecoverable error.
 
+config BLUETOOTH_CONTROLLER_PROFILE_ISR
+	bool "Profile radio ISR"
+	help
+	  Turn on measurement of radio ISR latency, CPU usage and generation of
+	  controller event with these profiling data. The controller event
+	  contains current, minimum and maximum ISR entry latencies; and
+	  current, minimum and maximum ISR CPU use in micro-seconds.
 
 endif # BLUETOOTH_CONTROLLER
diff --git a/subsys/bluetooth/controller/hci/hci.c b/subsys/bluetooth/controller/hci/hci.c
index b9307f363e5..956abbc0b8a 100644
--- a/subsys/bluetooth/controller/hci/hci.c
+++ b/subsys/bluetooth/controller/hci/hci.c
@@ -1103,6 +1103,7 @@ static void encode_control(struct radio_pdu_node_rx *node_rx,
 		/** @todo */
 		return;
 
+#if defined(CONFIG_BLUETOOTH_CONTROLLER_PROFILE_ISR)
 	case NODE_RX_TYPE_PROFILE:
 		/** @todo */
 		BT_INFO("l: %d, %d, %d; t: %d, %d, %d.",
@@ -1113,6 +1114,7 @@ static void encode_control(struct radio_pdu_node_rx *node_rx,
 			pdu_data->payload.profile.min,
 			pdu_data->payload.profile.max);
 		return;
+#endif /* CONFIG_BLUETOOTH_CONTROLLER_PROFILE_ISR */
 
 	default:
 		LL_ASSERT(0);
diff --git a/subsys/bluetooth/controller/ll/ctrl.c b/subsys/bluetooth/controller/ll/ctrl.c
index 5d1faee0a71..afc5b2bdb9c 100644
--- a/subsys/bluetooth/controller/ll/ctrl.c
+++ b/subsys/bluetooth/controller/ll/ctrl.c
@@ -60,7 +60,6 @@
 
 #define XTAL_ADVANCED		1
 #define SCHED_ADVANCED		1
-#define PROFILE_ISR		0
 #define FAST_ENC_PROCEDURE	0
 #define SILENT_CONNECTION	0
 
@@ -1950,7 +1949,8 @@ static inline void isr_rx_conn(uint8_t crc_ok, uint8_t trx_done,
 	struct pdu_data *pdu_data_rx;
 	struct pdu_data *pdu_data_tx;
 	uint8_t crc_close = 0;
-#if PROFILE_ISR
+
+#if defined(CONFIG_BLUETOOTH_CONTROLLER_PROFILE_ISR)
 	static uint8_t s_lmax;
 	static uint8_t s_lmin = (uint8_t) -1;
 	static uint8_t s_lprv;
@@ -1960,7 +1960,7 @@ static inline void isr_rx_conn(uint8_t crc_ok, uint8_t trx_done,
 	uint32_t sample;
 	uint8_t latency, elapsed, prv;
 	uint8_t chg = 0;
-#endif
+#endif /* CONFIG_BLUETOOTH_CONTROLLER_PROFILE_ISR */
 
 	/* Collect RSSI for connection */
 	if (_radio.packet_counter == 0) {
@@ -2075,7 +2075,7 @@ static inline void isr_rx_conn(uint8_t crc_ok, uint8_t trx_done,
 
 isr_rx_conn_exit:
 
-#if PROFILE_ISR
+#if defined(CONFIG_BLUETOOTH_CONTROLLER_PROFILE_ISR)
 	/* get the ISR latency sample */
 	sample = radio_tmr_sample_get();
 
@@ -2145,7 +2145,7 @@ isr_rx_conn_exit:
 			packet_rx_enqueue();
 		}
 	}
-#endif
+#endif /* CONFIG_BLUETOOTH_CONTROLLER_PROFILE_ISR */
 
 	return;
 }
@@ -2629,12 +2629,14 @@ static void isr(void)
 	/* Read radio status and events */
 	trx_done = radio_is_done();
 	if (trx_done) {
-#if PROFILE_ISR
+
+#if defined(CONFIG_BLUETOOTH_CONTROLLER_PROFILE_ISR)
 		/* sample the packet timer here, use it to calculate ISR latency
 		 * and generate the profiling event at the end of the ISR.
 		 */
 		radio_tmr_sample();
-#endif
+#endif /* CONFIG_BLUETOOTH_CONTROLLER_PROFILE_ISR */
+
 		crc_ok = radio_crc_is_valid();
 		devmatch_ok = radio_filter_has_match();
 		irkmatch_ok = radio_ar_has_match();
@@ -7604,13 +7606,17 @@ void radio_rx_dequeue(void)
 
 	switch (radio_pdu_node_rx->hdr.type) {
 	case NODE_RX_TYPE_DC_PDU:
-	case NODE_RX_TYPE_PROFILE:
 	case NODE_RX_TYPE_REPORT:
 	case NODE_RX_TYPE_CONNECTION:
 	case NODE_RX_TYPE_CONN_UPDATE:
 	case NODE_RX_TYPE_ENC_REFRESH:
 	case NODE_RX_TYPE_APTO:
 	case NODE_RX_TYPE_RSSI:
+
+#if defined(CONFIG_BLUETOOTH_CONTROLLER_PROFILE_ISR)
+	case NODE_RX_TYPE_PROFILE:
+#endif /* CONFIG_BLUETOOTH_CONTROLLER_PROFILE_ISR */
+
 		/* release data link credit quota */
 		LL_ASSERT(_radio.link_rx_data_quota <
 			  (_radio.packet_rx_count - 1));
@@ -7642,13 +7648,17 @@ void radio_rx_mem_release(struct radio_pdu_node_rx **radio_pdu_node_rx)
 
 		switch (_radio_pdu_node_rx_free->hdr.type) {
 		case NODE_RX_TYPE_DC_PDU:
-		case NODE_RX_TYPE_PROFILE:
 		case NODE_RX_TYPE_REPORT:
 		case NODE_RX_TYPE_CONNECTION:
 		case NODE_RX_TYPE_CONN_UPDATE:
 		case NODE_RX_TYPE_ENC_REFRESH:
 		case NODE_RX_TYPE_APTO:
 		case NODE_RX_TYPE_RSSI:
+
+#if defined(CONFIG_BLUETOOTH_CONTROLLER_PROFILE_ISR)
+		case NODE_RX_TYPE_PROFILE:
+#endif /* CONFIG_BLUETOOTH_CONTROLLER_PROFILE_ISR */
+
 			mem_release(_radio_pdu_node_rx_free,
 				    &_radio.pkt_rx_data_free);
 			break;
diff --git a/subsys/bluetooth/controller/ll/ctrl.h b/subsys/bluetooth/controller/ll/ctrl.h
index b435d32b616..9b60b53de04 100644
--- a/subsys/bluetooth/controller/ll/ctrl.h
+++ b/subsys/bluetooth/controller/ll/ctrl.h
@@ -180,7 +180,6 @@ struct radio_pdu_node_tx {
 enum radio_pdu_node_rx_type {
 	NODE_RX_TYPE_NONE,
 	NODE_RX_TYPE_DC_PDU,
-	NODE_RX_TYPE_PROFILE,
 	NODE_RX_TYPE_REPORT,
 	NODE_RX_TYPE_CONNECTION,
 	NODE_RX_TYPE_TERMINATE,
@@ -188,6 +187,9 @@ enum radio_pdu_node_rx_type {
 	NODE_RX_TYPE_ENC_REFRESH,
 	NODE_RX_TYPE_APTO,
 	NODE_RX_TYPE_RSSI,
+#if defined(CONFIG_BLUETOOTH_CONTROLLER_PROFILE_ISR)
+	NODE_RX_TYPE_PROFILE,
+#endif /* CONFIG_BLUETOOTH_CONTROLLER_PROFILE_ISR */
 };
 
 struct radio_pdu_node_rx_hdr {
diff --git a/subsys/bluetooth/controller/ll/pdu.h b/subsys/bluetooth/controller/ll/pdu.h
index a5b6a77a010..ac09edd994b 100644
--- a/subsys/bluetooth/controller/ll/pdu.h
+++ b/subsys/bluetooth/controller/ll/pdu.h
@@ -232,6 +232,7 @@ struct pdu_data_llctrl {
 	} __packed ctrldata;
 } __packed;
 
+#if defined(CONFIG_BLUETOOTH_CONTROLLER_PROFILE_ISR)
 struct profile {
 	uint8_t lcur;
 	uint8_t lmin;
@@ -240,6 +241,7 @@ struct profile {
 	uint8_t min;
 	uint8_t max;
 } __packed;
+#endif /* CONFIG_BLUETOOTH_CONTROLLER_PROFILE_ISR */
 
 struct pdu_data {
 	uint8_t ll_id:2;
@@ -256,7 +258,9 @@ struct pdu_data {
 		uint8_t lldata[1];
 		struct pdu_data_llctrl llctrl;
 		uint8_t rssi;
+#if defined(CONFIG_BLUETOOTH_CONTROLLER_PROFILE_ISR)
 		struct profile profile;
+#endif /* CONFIG_BLUETOOTH_CONTROLLER_PROFILE_ISR */
 	} __packed payload;
 } __packed;
 
diff --git a/tests/bluetooth/init/prj_controller_dbg.conf b/tests/bluetooth/init/prj_controller_dbg.conf
index b90f28f003c..1e79504f997 100644
--- a/tests/bluetooth/init/prj_controller_dbg.conf
+++ b/tests/bluetooth/init/prj_controller_dbg.conf
@@ -1,5 +1,6 @@
 CONFIG_BLUETOOTH=y
 CONFIG_BLUETOOTH_CONTROLLER=y
+CONFIG_BLUETOOTH_CONTROLLER_PROFILE_ISR=y
 CONFIG_BLUETOOTH_PERIPHERAL=y
 CONFIG_BLUETOOTH_CENTRAL=y
 CONFIG_BLUETOOTH_SMP=y