diff --git a/drivers/serial/Kconfig.nrfx b/drivers/serial/Kconfig.nrfx
index 21a657fbaf4..8995b6b9fbf 100644
--- a/drivers/serial/Kconfig.nrfx
+++ b/drivers/serial/Kconfig.nrfx
@@ -31,6 +31,8 @@ config UART_NRFX_UARTE
 config UART_NRFX_UARTE_LEGACY_SHIM
 	bool "Legacy UARTE shim"
 	depends on UART_NRFX_UARTE
+	# NRF54L15 need new UARTE driver
+	depends on !SOC_SERIES_NRF54LX
 	# New shim takes more ROM. Until it is fixed use legacy shim.
 	default y
 
@@ -64,6 +66,31 @@ nrfx_uart_num = 3
 rsource "Kconfig.nrfx_uart_instance"
 endif
 
+if HAS_HW_NRF_UARTE00
+nrfx_uart_num = 00
+rsource "Kconfig.nrfx_uart_instance"
+endif
+
+if HAS_HW_NRF_UARTE20
+nrfx_uart_num = 20
+rsource "Kconfig.nrfx_uart_instance"
+endif
+
+if HAS_HW_NRF_UARTE21
+nrfx_uart_num = 21
+rsource "Kconfig.nrfx_uart_instance"
+endif
+
+if HAS_HW_NRF_UARTE22
+nrfx_uart_num = 22
+rsource "Kconfig.nrfx_uart_instance"
+endif
+
+if HAS_HW_NRF_UARTE30
+nrfx_uart_num = 30
+rsource "Kconfig.nrfx_uart_instance"
+endif
+
 config NRFX_TIMER0
 	default y
 	depends on UART_0_NRF_HW_ASYNC_TIMER = 0 \
diff --git a/drivers/serial/Kconfig.nrfx_uart_instance b/drivers/serial/Kconfig.nrfx_uart_instance
index 76f74caa038..718631a4d09 100644
--- a/drivers/serial/Kconfig.nrfx_uart_instance
+++ b/drivers/serial/Kconfig.nrfx_uart_instance
@@ -20,6 +20,7 @@ config UART_$(nrfx_uart_num)_ASYNC
 
 config UART_$(nrfx_uart_num)_ENHANCED_POLL_OUT
 	bool "Efficient poll out on port $(nrfx_uart_num)"
+	depends on !SOC_SERIES_NRF54LX
 	default y
 	depends on HAS_HW_NRF_UARTE$(nrfx_uart_num)
 	select NRFX_PPI if HAS_HW_NRF_PPI