diff --git a/drivers/i2c/Kconfig.stm32 b/drivers/i2c/Kconfig.stm32
index 90d1febceb1..2666b590a9e 100644
--- a/drivers/i2c/Kconfig.stm32
+++ b/drivers/i2c/Kconfig.stm32
@@ -1,9 +1,12 @@
 # Copyright (c) 2018 Intel Corporation
 # SPDX-License-Identifier: Apache-2.0
 
+DT_COMPAT_ST_STM32_I2C_V1 := st,stm32-i2c-v1
+DT_COMPAT_ST_STM32_I2C_V2 := st,stm32-i2c-v2
+
 menuconfig I2C_STM32
 	bool "STM32 I2C driver"
-	depends on SOC_FAMILY_STM32
+	default $(dt_compat_enabled,$(DT_COMPAT_ST_STM32_I2C_V1)) || $(dt_compat_enabled,$(DT_COMPAT_ST_STM32_I2C_V2))
 	help
 	  Enable I2C support on the STM32 SoCs
 
@@ -11,7 +14,7 @@ if I2C_STM32
 
 config I2C_STM32_V1
 	bool
-	depends on SOC_SERIES_STM32F1X || SOC_SERIES_STM32F4X || SOC_SERIES_STM32L1X
+	default $(dt_compat_enabled,$(DT_COMPAT_ST_STM32_I2C_V1))
 	select USE_STM32_LL_I2C
 	select I2C_STM32_INTERRUPT if I2C_SLAVE
 	help
@@ -20,10 +23,7 @@ config I2C_STM32_V1
 
 config I2C_STM32_V2
 	bool
-	depends on (SOC_SERIES_STM32F0X || SOC_SERIES_STM32F3X || \
-	SOC_SERIES_STM32F7X || SOC_SERIES_STM32L0X || SOC_SERIES_STM32L4X || \
-	SOC_SERIES_STM32WBX || SOC_SERIES_STM32MP1X || SOC_SERIES_STM32G0X || \
-	SOC_SERIES_STM32G4X || SOC_SERIES_STM32H7X)
+	default $(dt_compat_enabled,$(DT_COMPAT_ST_STM32_I2C_V2))
 	select USE_STM32_LL_I2C
 	select USE_STM32_LL_RCC if SOC_SERIES_STM32F0X || SOC_SERIES_STM32F3X
 	select I2C_STM32_INTERRUPT if I2C_SLAVE
diff --git a/soc/arm/st_stm32/common/Kconfig.defconfig.series b/soc/arm/st_stm32/common/Kconfig.defconfig.series
index a1f19708992..68e9ac1a856 100644
--- a/soc/arm/st_stm32/common/Kconfig.defconfig.series
+++ b/soc/arm/st_stm32/common/Kconfig.defconfig.series
@@ -49,10 +49,6 @@ config SPI_STM32
 	default y
 	depends on SPI
 
-config I2C_STM32
-	default y
-	depends on I2C
-
 config USB_DC_STM32
 	default y
 	depends on USB
diff --git a/soc/arm/st_stm32/stm32f0/Kconfig.defconfig.series b/soc/arm/st_stm32/stm32f0/Kconfig.defconfig.series
index 75d0df2237f..b162a0b6879 100644
--- a/soc/arm/st_stm32/stm32f0/Kconfig.defconfig.series
+++ b/soc/arm/st_stm32/stm32f0/Kconfig.defconfig.series
@@ -12,10 +12,6 @@ source "soc/arm/st_stm32/stm32f0/Kconfig.defconfig.stm32f0*"
 config SOC_SERIES
 	default "stm32f0"
 
-config I2C_STM32_V2
-	default y
-	depends on I2C_STM32
-
 config DMA_STM32_V2
 	default y
 	depends on DMA_STM32
diff --git a/soc/arm/st_stm32/stm32f1/Kconfig.defconfig.series b/soc/arm/st_stm32/stm32f1/Kconfig.defconfig.series
index ef11b69cff1..245d6176a15 100644
--- a/soc/arm/st_stm32/stm32f1/Kconfig.defconfig.series
+++ b/soc/arm/st_stm32/stm32f1/Kconfig.defconfig.series
@@ -12,10 +12,6 @@ source "soc/arm/st_stm32/stm32f1/Kconfig.defconfig.stm32f1*"
 config SOC_SERIES
 	default "stm32f1"
 
-config I2C_STM32_V1
-	default y
-	depends on I2C_STM32
-
 config DMA_STM32_V2
 	default y
 	depends on DMA_STM32
diff --git a/soc/arm/st_stm32/stm32f3/Kconfig.defconfig.series b/soc/arm/st_stm32/stm32f3/Kconfig.defconfig.series
index 4981dcad453..12d203bb0ab 100644
--- a/soc/arm/st_stm32/stm32f3/Kconfig.defconfig.series
+++ b/soc/arm/st_stm32/stm32f3/Kconfig.defconfig.series
@@ -12,10 +12,6 @@ source "soc/arm/st_stm32/stm32f3/Kconfig.defconfig.stm32f3*"
 config SOC_SERIES
 	default "stm32f3"
 
-config I2C_STM32_V2
-	default y
-	depends on I2C_STM32
-
 config DMA_STM32_V2
 	default y
 	depends on DMA_STM32
diff --git a/soc/arm/st_stm32/stm32f4/Kconfig.defconfig.series b/soc/arm/st_stm32/stm32f4/Kconfig.defconfig.series
index 9661861cd92..cd4bd15d1c8 100644
--- a/soc/arm/st_stm32/stm32f4/Kconfig.defconfig.series
+++ b/soc/arm/st_stm32/stm32f4/Kconfig.defconfig.series
@@ -12,10 +12,6 @@ source "soc/arm/st_stm32/stm32f4/Kconfig.defconfig.stm32f4*"
 config SOC_SERIES
 	default "stm32f4"
 
-config I2C_STM32_V1
-	default y
-	depends on I2C_STM32
-
 config DMA_STM32_V1
 	default y
 	depends on DMA_STM32
diff --git a/soc/arm/st_stm32/stm32f7/Kconfig.defconfig.series b/soc/arm/st_stm32/stm32f7/Kconfig.defconfig.series
index 14b60e9b291..789f7930ebb 100644
--- a/soc/arm/st_stm32/stm32f7/Kconfig.defconfig.series
+++ b/soc/arm/st_stm32/stm32f7/Kconfig.defconfig.series
@@ -12,10 +12,6 @@ source "soc/arm/st_stm32/stm32f7/Kconfig.defconfig.stm32f7*"
 config SOC_SERIES
 	default "stm32f7"
 
-config I2C_STM32_V2
-	default y
-	depends on I2C_STM32
-
 config DMA_STM32_V1
 	default y
 	depends on DMA_STM32
diff --git a/soc/arm/st_stm32/stm32g0/Kconfig.defconfig.series b/soc/arm/st_stm32/stm32g0/Kconfig.defconfig.series
index 4d58e046c58..039b6900cc6 100644
--- a/soc/arm/st_stm32/stm32g0/Kconfig.defconfig.series
+++ b/soc/arm/st_stm32/stm32g0/Kconfig.defconfig.series
@@ -11,8 +11,4 @@ source "soc/arm/st_stm32/stm32g0/Kconfig.defconfig.stm32g0*"
 config SOC_SERIES
 	default "stm32g0"
 
-config I2C_STM32_V2
-	default y
-	depends on I2C_STM32
-
 endif # SOC_SERIES_STM32G0X
diff --git a/soc/arm/st_stm32/stm32g4/Kconfig.defconfig.series b/soc/arm/st_stm32/stm32g4/Kconfig.defconfig.series
index 3cfd05713da..b0043b2956c 100644
--- a/soc/arm/st_stm32/stm32g4/Kconfig.defconfig.series
+++ b/soc/arm/st_stm32/stm32g4/Kconfig.defconfig.series
@@ -10,8 +10,4 @@ source "soc/arm/st_stm32/stm32g4/Kconfig.defconfig.stm32g4*"
 config SOC_SERIES
 	default "stm32g4"
 
-config I2C_STM32_V2
-	default y
-	depends on I2C_STM32
-
 endif # SOC_SERIES_STM32G4X
diff --git a/soc/arm/st_stm32/stm32h7/Kconfig.defconfig.series b/soc/arm/st_stm32/stm32h7/Kconfig.defconfig.series
index 314c0008f07..665f05e1315 100644
--- a/soc/arm/st_stm32/stm32h7/Kconfig.defconfig.series
+++ b/soc/arm/st_stm32/stm32h7/Kconfig.defconfig.series
@@ -12,8 +12,4 @@ source "soc/arm/st_stm32/stm32h7/Kconfig.defconfig.stm32h7*"
 config SOC_SERIES
 	default "stm32h7"
 
-config I2C_STM32_V2
-	default y
-	depends on I2C_STM32
-
 endif # SOC_SERIES_STM32H7X
diff --git a/soc/arm/st_stm32/stm32l0/Kconfig.defconfig.series b/soc/arm/st_stm32/stm32l0/Kconfig.defconfig.series
index 0bf5da3435b..fbc2a8f1af6 100644
--- a/soc/arm/st_stm32/stm32l0/Kconfig.defconfig.series
+++ b/soc/arm/st_stm32/stm32l0/Kconfig.defconfig.series
@@ -12,10 +12,6 @@ source "soc/arm/st_stm32/stm32l0/Kconfig.defconfig.stm32l0*"
 config SOC_SERIES
 	default "stm32l0"
 
-config I2C_STM32_V2
-	default y
-	depends on I2C_STM32
-
 config DMA_STM32_V2
 	default y
 	depends on DMA_STM32
diff --git a/soc/arm/st_stm32/stm32l0/soc.h b/soc/arm/st_stm32/stm32l0/soc.h
index 9a254a9cc6e..244cd3ae23d 100644
--- a/soc/arm/st_stm32/stm32l0/soc.h
+++ b/soc/arm/st_stm32/stm32l0/soc.h
@@ -44,7 +44,7 @@
 #include <stm32l0xx_ll_rcc.h>
 #endif /* CONFIG_CLOCK_CONTROL_STM32_CUBE */
 
-#ifdef CONFIG_I2C_STM32_V2
+#ifdef CONFIG_I2C_STM32
 #include <stm32l0xx_ll_i2c.h>
 #endif
 
diff --git a/soc/arm/st_stm32/stm32l1/Kconfig.defconfig.series b/soc/arm/st_stm32/stm32l1/Kconfig.defconfig.series
index d77d7ec8f49..c2f50628a63 100644
--- a/soc/arm/st_stm32/stm32l1/Kconfig.defconfig.series
+++ b/soc/arm/st_stm32/stm32l1/Kconfig.defconfig.series
@@ -10,8 +10,4 @@ source "soc/arm/st_stm32/stm32l1/Kconfig.defconfig.stm32l1*"
 config SOC_SERIES
 	default "stm32l1"
 
-config I2C_STM32_V1
-	default y
-	depends on I2C_STM32
-
 endif # SOC_SERIES_STM32L1X
diff --git a/soc/arm/st_stm32/stm32l4/Kconfig.defconfig.series b/soc/arm/st_stm32/stm32l4/Kconfig.defconfig.series
index e6f3f06016c..899ec412d52 100644
--- a/soc/arm/st_stm32/stm32l4/Kconfig.defconfig.series
+++ b/soc/arm/st_stm32/stm32l4/Kconfig.defconfig.series
@@ -13,10 +13,6 @@ source "soc/arm/st_stm32/stm32l4/Kconfig.defconfig.stm32l4*"
 config SOC_SERIES
 	default "stm32l4"
 
-config I2C_STM32_V2
-	default y
-	depends on I2C_STM32
-
 config DMA_STM32_V2
 	default y
 	depends on DMA_STM32
diff --git a/soc/arm/st_stm32/stm32mp1/Kconfig.defconfig.series b/soc/arm/st_stm32/stm32mp1/Kconfig.defconfig.series
index 5a10cdb06bf..9c980c86d3e 100644
--- a/soc/arm/st_stm32/stm32mp1/Kconfig.defconfig.series
+++ b/soc/arm/st_stm32/stm32mp1/Kconfig.defconfig.series
@@ -14,8 +14,4 @@ config IPM_STM32_IPCC
 	default y
 	depends on IPM
 
-config I2C_STM32_V2
-	default y
-	depends on I2C_STM32
-
 endif # SOC_SERIES_STM32MP1X
diff --git a/soc/arm/st_stm32/stm32wb/Kconfig.defconfig.series b/soc/arm/st_stm32/stm32wb/Kconfig.defconfig.series
index 9083bcb32cd..9a5459a7b0c 100644
--- a/soc/arm/st_stm32/stm32wb/Kconfig.defconfig.series
+++ b/soc/arm/st_stm32/stm32wb/Kconfig.defconfig.series
@@ -10,8 +10,4 @@ source "soc/arm/st_stm32/stm32wb/Kconfig.defconfig.stm32wb*"
 config SOC_SERIES
 	default "stm32wb"
 
-config I2C_STM32_V2
-	default y
-	depends on I2C_STM32
-
 endif # SOC_SERIES_STM32WBX