diff --git a/tests/subsys/openthread/testcase.yaml b/tests/subsys/openthread/testcase.yaml
index c019aa9a8c5..163024d86b7 100644
--- a/tests/subsys/openthread/testcase.yaml
+++ b/tests/subsys/openthread/testcase.yaml
@@ -1,9 +1,10 @@
 common:
   platform_allow:
-    - native_posix
-    - native_posix/native/64
     - native_sim
     - native_sim/native/64
+  platform_exclude:
+    - native_posix/native/64
+    - native_posix
   integration_platforms:
     - native_sim
   tags: