diff --git a/subsys/bluetooth/controller/ll_sw/lll_conn.h b/subsys/bluetooth/controller/ll_sw/lll_conn.h
index 7fb326e5bd6..0564c61b893 100644
--- a/subsys/bluetooth/controller/ll_sw/lll_conn.h
+++ b/subsys/bluetooth/controller/ll_sw/lll_conn.h
@@ -59,6 +59,7 @@ struct lll_conn {
 	union {
 		struct {
 			uint8_t initiated:1;
+			uint8_t cancelled:1;
 		} master;
 #if defined(CONFIG_BT_PERIPHERAL)
 		struct {
diff --git a/subsys/bluetooth/controller/ll_sw/lll_scan.h b/subsys/bluetooth/controller/ll_sw/lll_scan.h
index 972d3332295..767e9b19370 100644
--- a/subsys/bluetooth/controller/ll_sw/lll_scan.h
+++ b/subsys/bluetooth/controller/ll_sw/lll_scan.h
@@ -12,7 +12,7 @@ struct lll_scan {
 	 *       check ull_conn_setup how it access the connection LLL
 	 *       context.
 	 */
-	struct lll_conn *conn;
+	struct lll_conn *volatile conn;
 
 	uint8_t  adv_addr[BDADDR_SIZE];
 	uint32_t conn_win_offset_us;
diff --git a/subsys/bluetooth/controller/ll_sw/nordic/lll/lll_scan.c b/subsys/bluetooth/controller/ll_sw/nordic/lll/lll_scan.c
index 33f46bedf64..f7a7507c58f 100644
--- a/subsys/bluetooth/controller/ll_sw/nordic/lll/lll_scan.c
+++ b/subsys/bluetooth/controller/ll_sw/nordic/lll/lll_scan.c
@@ -140,7 +140,9 @@ static int prepare_cb(struct lll_prepare_param *p)
 	/* Check if stopped (on connection establishment race between LLL and
 	 * ULL.
 	 */
-	if (unlikely(lll->conn && lll->conn->master.initiated)) {
+	if (unlikely(lll->conn &&
+		     (lll->conn->master.initiated ||
+		      lll->conn->master.cancelled))) {
 		int err;
 
 		err = lll_hfclock_off();
@@ -779,7 +781,7 @@ static inline int isr_rx_pdu(struct lll_scan *lll, struct pdu_adv *pdu_adv_rx,
 	if (0) {
 #if defined(CONFIG_BT_CENTRAL)
 	/* Initiator */
-	} else if (lll->conn &&
+	} else if (lll->conn && !lll->conn->master.cancelled &&
 		   isr_scan_init_check(lll, pdu_adv_rx, rl_idx)) {
 		struct lll_conn *lll_conn;
 		struct node_rx_ftr *ftr;
diff --git a/subsys/bluetooth/controller/ll_sw/ull_master.c b/subsys/bluetooth/controller/ll_sw/ull_master.c
index 550ed3d994d..e34c4e74741 100644
--- a/subsys/bluetooth/controller/ll_sw/ull_master.c
+++ b/subsys/bluetooth/controller/ll_sw/ull_master.c
@@ -222,6 +222,7 @@ uint8_t ll_create_connection(uint16_t scan_interval, uint16_t scan_window,
 	conn_lll->data_chan_use = 0;
 	conn_lll->role = 0;
 	conn_lll->master.initiated = 0;
+	conn_lll->master.cancelled = 0;
 	/* FIXME: END: Move to ULL? */
 #if defined(CONFIG_BT_CTLR_CONN_META)
 	memset(&conn_lll->conn_meta, 0, sizeof(conn_lll->conn_meta));
@@ -428,8 +429,28 @@ uint8_t ll_connect_disable(void **rx)
 		scan_lll = &scan->lll;
 	}
 
+	/* Check if initiator active */
 	conn_lll = scan_lll->conn;
 	if (!conn_lll) {
+		/* Scanning not associated with initiation of a connection or
+		 * connection setup already complete (was set to NULL in
+		 * ull_master_setup), but HCI event not processed by host.
+		 */
+		return BT_HCI_ERR_CMD_DISALLOWED;
+	}
+
+	/* Indicate to LLL that a cancellation is requested */
+	conn_lll->master.cancelled = 1U;
+	cpu_dmb();
+
+	/* Check if connection was established under race condition, i.e.
+	 * before the cancelled flag was set.
+	 */
+	conn_lll = scan_lll->conn;
+	if (!conn_lll) {
+		/* Connection setup completed on race condition with cancelled
+		 * flag, before it was set.
+		 */
 		return BT_HCI_ERR_CMD_DISALLOWED;
 	}