diff --git a/Kconfig.zephyr b/Kconfig.zephyr
index eb4399c297f..b315a0e7aad 100644
--- a/Kconfig.zephyr
+++ b/Kconfig.zephyr
@@ -429,7 +429,9 @@ endchoice
 
 config LTO
 	bool "Link Time Optimization [EXPERIMENTAL]"
-	depends on (!(GEN_ISR_TABLES || GEN_IRQ_VECTOR_TABLE) || ISR_TABLES_LOCAL_DECLARATION) && !NATIVE_LIBRARY
+	depends on !(GEN_ISR_TABLES || GEN_IRQ_VECTOR_TABLE) || ISR_TABLES_LOCAL_DECLARATION
+	depends on !NATIVE_LIBRARY
+	depends on !CODE_DATA_RELOCATION
 	select EXPERIMENTAL
 	help
 	  This option enables Link Time Optimization.