diff --git a/drivers/gpio/Kconfig.pca95xx b/drivers/gpio/Kconfig.pca95xx
index f2513bc3a33..7711b8b956a 100644
--- a/drivers/gpio/Kconfig.pca95xx
+++ b/drivers/gpio/Kconfig.pca95xx
@@ -15,3 +15,12 @@ config GPIO_PCA95XX_INIT_PRIORITY
 	depends on GPIO_PCA95XX
 	help
 	  Device driver initialization priority.
+
+config GPIO_PCA95XX_INTERRUPT
+	bool "Interrupt enable"
+	default n
+	depends on GPIO_PCA95XX
+	help
+	  Enable interrupt support in PCA95XX driver.
+	  Note that the PCA95XX cannot reliably detect
+	  short-pulse interrupts due to its design.
diff --git a/drivers/gpio/gpio_pca95xx.c b/drivers/gpio/gpio_pca95xx.c
index 426981a619c..70a0a1c84b1 100644
--- a/drivers/gpio/gpio_pca95xx.c
+++ b/drivers/gpio/gpio_pca95xx.c
@@ -1,5 +1,6 @@
 /*
  * Copyright (c) 2015 Intel Corporation.
+ * Copyright (c) 2020 Norbit ODM AS
  *
  * SPDX-License-Identifier: Apache-2.0
  */
@@ -53,6 +54,7 @@ LOG_MODULE_REGISTER(gpio_pca95xx);
 
 /* Driver flags */
 #define PCA_HAS_PUD			BIT(0)
+#define PCA_HAS_INTERRUPT		BIT(1)
 
 /** Configuration data */
 struct gpio_pca95xx_config {
@@ -66,6 +68,15 @@ struct gpio_pca95xx_config {
 	uint16_t i2c_slave_addr;
 
 	uint8_t capabilities;
+
+#ifdef CONFIG_GPIO_PCA95XX_INTERRUPT
+	/* Interrupt pin definition */
+	const char *int_gpio_port;
+
+	gpio_pin_t int_gpio_pin;
+
+	gpio_flags_t int_gpio_flags;
+#endif
 };
 
 /** Runtime driver data */
@@ -77,6 +88,7 @@ struct gpio_pca95xx_drv_data {
 	const struct device *i2c_master;
 
 	struct {
+		uint16_t input;
 		uint16_t output;
 		uint16_t dir;
 		uint16_t pud_en;
@@ -84,6 +96,28 @@ struct gpio_pca95xx_drv_data {
 	} reg_cache;
 
 	struct k_sem lock;
+
+#ifdef CONFIG_GPIO_PCA95XX_INTERRUPT
+	/* Self-reference to the driver instance */
+	const struct device *instance;
+
+	/* port ISR callback routine address */
+	sys_slist_t callbacks;
+
+	/* interrupt triggering pin masks */
+	struct {
+		uint16_t edge_rising;
+		uint16_t edge_falling;
+		uint16_t level_high;
+		uint16_t level_low;
+	} interrupts;
+
+	struct gpio_callback gpio_callback;
+
+	struct k_work interrupt_worker;
+
+	bool interrupt_active;
+#endif
 };
 
 /**
@@ -93,19 +127,20 @@ struct gpio_pca95xx_drv_data {
  *
  * @param dev Device struct of the PCA95XX.
  * @param reg Register to read (the PORT0 of the pair of registers).
+ * @param cache Pointer to the cache to be updated after successful read.
  * @param buf Buffer to read data into.
  *
  * @return 0 if successful, failed otherwise.
  */
 static int read_port_regs(const struct device *dev, uint8_t reg,
-			  uint16_t *buf)
+			  uint16_t *cache, uint16_t *buf)
 {
 	const struct gpio_pca95xx_config * const config = dev->config;
 	struct gpio_pca95xx_drv_data * const drv_data =
 		(struct gpio_pca95xx_drv_data * const)dev->data;
 	const struct device *i2c_master = drv_data->i2c_master;
 	uint16_t i2c_addr = config->i2c_slave_addr;
-	uint16_t port_data;
+	uint16_t port_data, value;
 	int ret;
 
 	ret = i2c_burst_read(i2c_master, i2c_addr, reg,
@@ -116,7 +151,9 @@ static int read_port_regs(const struct device *dev, uint8_t reg,
 		return ret;
 	}
 
-	*buf = sys_le16_to_cpu(port_data);
+	value = sys_le16_to_cpu(port_data);
+	*cache = value;
+	*buf = value;
 
 	LOG_DBG("PCA95XX[0x%X]: Read: REG[0x%X] = 0x%X, REG[0x%X] = 0x%X",
 		i2c_addr, reg, (*buf & 0xFF), (reg + 1), (*buf >> 8));
@@ -165,6 +202,15 @@ static int write_port_regs(const struct device *dev, uint8_t reg,
 	return ret;
 }
 
+static inline int update_input_regs(const struct device *dev, uint16_t *buf)
+{
+	struct gpio_pca95xx_drv_data * const drv_data =
+		(struct gpio_pca95xx_drv_data * const)dev->data;
+
+	return read_port_regs(dev, REG_INPUT_PORT0,
+			      &drv_data->reg_cache.input, buf);
+}
+
 static inline int update_output_regs(const struct device *dev, uint16_t value)
 {
 	struct gpio_pca95xx_drv_data * const drv_data =
@@ -374,7 +420,7 @@ static int gpio_pca95xx_port_get_raw(const struct device *dev,
 
 	k_sem_take(&drv_data->lock, K_FOREVER);
 
-	ret = read_port_regs(dev, REG_INPUT_PORT0, &buf);
+	ret = update_input_regs(dev, &buf);
 	if (ret != 0) {
 		goto done;
 	}
@@ -448,14 +494,173 @@ static int gpio_pca95xx_port_toggle_bits(const struct device *dev,
 	return ret;
 }
 
+#ifdef CONFIG_GPIO_PCA95XX_INTERRUPT
+static void gpio_pca95xx_interrupt_worker(struct k_work *work)
+{
+	struct gpio_pca95xx_drv_data * const drv_data = CONTAINER_OF(
+		work, struct gpio_pca95xx_drv_data, interrupt_worker);
+	uint16_t input_new, input_cache, changed_pins, trig_edge;
+	uint16_t trig_level = 0;
+	uint32_t triggered_int = 0;
+	int ret;
+
+	k_sem_take(&drv_data->lock, K_FOREVER);
+
+	input_cache = drv_data->reg_cache.input;
+
+	ret = update_input_regs(drv_data->instance, &input_new);
+	if (ret == 0) {
+		/* Note: PCA Interrupt status is cleared by reading inputs */
+
+		changed_pins = (input_cache ^ input_new);
+
+		trig_edge = (changed_pins & input_new &
+			     drv_data->interrupts.edge_rising);
+		trig_edge |= (changed_pins & input_cache &
+			      drv_data->interrupts.edge_falling);
+		trig_level = (input_new & drv_data->interrupts.level_high);
+		trig_level |= (~input_new & drv_data->interrupts.level_low);
+
+		triggered_int = (trig_edge | trig_level);
+	}
+
+	k_sem_give(&drv_data->lock);
+
+	if (triggered_int != 0) {
+		gpio_fire_callbacks(&drv_data->callbacks, drv_data->instance,
+				    triggered_int);
+	}
+
+	/* Emulate level triggering */
+	if (trig_level != 0) {
+		/* Reschedule worker */
+		k_work_submit(&drv_data->interrupt_worker);
+	}
+}
+
+static void gpio_pca95xx_interrupt_callback(const struct device *dev,
+					    struct gpio_callback *cb,
+					    gpio_port_pins_t pins)
+{
+	struct gpio_pca95xx_drv_data * const drv_data =
+		CONTAINER_OF(cb, struct gpio_pca95xx_drv_data, gpio_callback);
+
+	ARG_UNUSED(pins);
+
+	/* Cannot read PCA95xx registers from ISR context, queue worker */
+	k_work_submit(&drv_data->interrupt_worker);
+}
+#endif /* CONFIG_GPIO_PCA95XX_INTERRUPT */
+
 static int gpio_pca95xx_pin_interrupt_configure(const struct device *dev,
 						  gpio_pin_t pin,
 						  enum gpio_int_mode mode,
 						  enum gpio_int_trig trig)
 {
-	return -ENOTSUP;
+	int ret = 0;
+
+	if (!IS_ENABLED(CONFIG_GPIO_PCA95XX_INTERRUPT)
+	    && (mode != GPIO_INT_MODE_DISABLED)) {
+		return -ENOTSUP;
+	}
+
+#ifdef CONFIG_GPIO_PCA95XX_INTERRUPT
+	const struct gpio_pca95xx_config * const config = dev->config;
+	struct gpio_pca95xx_drv_data * const drv_data =
+		(struct gpio_pca95xx_drv_data * const)dev->data;
+	const struct device *int_gpio_dev;
+	uint16_t reg;
+	bool enabled, edge, level, active;
+
+	/* Check if GPIO port supports interrupts */
+	if ((config->capabilities & PCA_HAS_INTERRUPT) == 0U) {
+		return -ENOTSUP;
+	}
+
+	/* Check for an invalid pin number */
+	if (BIT(pin) > config->common.port_pin_mask) {
+		return -EINVAL;
+	}
+
+	/* Check configured pin direction */
+	if ((mode != GPIO_INT_MODE_DISABLED) &&
+	    (BIT(pin) & drv_data->reg_cache.dir) != BIT(pin)) {
+		LOG_ERR("PCA95XX[0x%X]: output pin cannot trigger interrupt",
+			config->i2c_slave_addr);
+		return -ENOTSUP;
+	}
+
+	k_sem_take(&drv_data->lock, K_FOREVER);
+
+	/* Update interrupt masks */
+	enabled = ((mode & GPIO_INT_MODE_DISABLED) == 0U);
+	edge = (mode == GPIO_INT_MODE_EDGE);
+	level = (mode == GPIO_INT_MODE_LEVEL);
+	WRITE_BIT(drv_data->interrupts.edge_rising, pin, (enabled &&
+		edge && ((trig & GPIO_INT_TRIG_HIGH) == GPIO_INT_TRIG_HIGH)));
+	WRITE_BIT(drv_data->interrupts.edge_falling, pin, (enabled &&
+		edge && ((trig & GPIO_INT_TRIG_LOW) == GPIO_INT_TRIG_LOW)));
+	WRITE_BIT(drv_data->interrupts.level_high, pin, (enabled &&
+		level && ((trig & GPIO_INT_TRIG_HIGH) == GPIO_INT_TRIG_HIGH)));
+	WRITE_BIT(drv_data->interrupts.level_low, pin, (enabled &&
+		level && ((trig & GPIO_INT_TRIG_LOW) == GPIO_INT_TRIG_LOW)));
+
+	active = ((drv_data->interrupts.edge_rising ||
+		   drv_data->interrupts.edge_falling ||
+		   drv_data->interrupts.level_high ||
+		   drv_data->interrupts.level_low) > 0);
+
+	/* Enable / disable interrupt as needed */
+	if (active != drv_data->interrupt_active) {
+		int_gpio_dev = device_get_binding(config->int_gpio_port);
+		ret = gpio_pin_interrupt_configure(int_gpio_dev,
+			config->int_gpio_pin, (active ?
+				GPIO_INT_EDGE_TO_ACTIVE :
+				GPIO_INT_MODE_DISABLED));
+		if (ret != 0) {
+			LOG_ERR("PCA95XX[0x%X]: failed to configure interrupt "
+				"on pin %d (%d)", config->i2c_slave_addr,
+				config->int_gpio_pin, ret);
+			goto err;
+		}
+		drv_data->interrupt_active = active;
+
+		if (active) {
+			/* Read current status to reset any
+			 * active signal on INT line
+			 */
+			update_input_regs(dev, &reg);
+		}
+	}
+
+err:
+	k_sem_give(&drv_data->lock);
+#endif /* CONFIG_GPIO_PCA95XX_INTERRUPT */
+	return ret;
 }
 
+#ifdef CONFIG_GPIO_PCA95XX_INTERRUPT
+static int gpio_pca95xx_manage_callback(const struct device *dev,
+					struct gpio_callback *callback,
+					bool set)
+{
+	const struct gpio_pca95xx_config * const config = dev->config;
+	struct gpio_pca95xx_drv_data * const drv_data =
+		(struct gpio_pca95xx_drv_data * const)dev->data;
+
+	if ((config->capabilities & PCA_HAS_INTERRUPT) == 0U) {
+		return -ENOTSUP;
+	}
+
+	k_sem_take(&drv_data->lock, K_FOREVER);
+
+	gpio_manage_callback(&drv_data->callbacks, callback, set);
+
+	k_sem_give(&drv_data->lock);
+	return 0;
+}
+#endif
+
 static const struct gpio_driver_api gpio_pca95xx_drv_api_funcs = {
 	.pin_configure = gpio_pca95xx_config,
 	.port_get_raw = gpio_pca95xx_port_get_raw,
@@ -464,6 +669,9 @@ static const struct gpio_driver_api gpio_pca95xx_drv_api_funcs = {
 	.port_clear_bits_raw = gpio_pca95xx_port_clear_bits_raw,
 	.port_toggle_bits = gpio_pca95xx_port_toggle_bits,
 	.pin_interrupt_configure = gpio_pca95xx_pin_interrupt_configure,
+#ifdef CONFIG_GPIO_PCA95XX_INTERRUPT
+	.manage_callback = gpio_pca95xx_manage_callback,
+#endif
 };
 
 /**
@@ -488,6 +696,45 @@ static int gpio_pca95xx_init(const struct device *dev)
 
 	k_sem_init(&drv_data->lock, 1, 1);
 
+#ifdef CONFIG_GPIO_PCA95XX_INTERRUPT
+	/* Check if GPIO port supports interrupts */
+	if ((config->capabilities & PCA_HAS_INTERRUPT) != 0) {
+		const struct device *int_gpio_dev;
+		int ret;
+
+		/* Store self-reference for interrupt handling */
+		drv_data->instance = dev;
+
+		/* Prepare interrupt worker */
+		k_work_init(&drv_data->interrupt_worker,
+			    gpio_pca95xx_interrupt_worker);
+
+		/* Configure GPIO interrupt pin */
+		int_gpio_dev = device_get_binding(config->int_gpio_port);
+		if (int_gpio_dev == NULL) {
+			LOG_ERR("PCA95XX[0x%X]: error getting interrupt GPIO"
+				" device (%s)", config->i2c_slave_addr,
+				config->int_gpio_port);
+			return -ENODEV;
+		}
+
+		ret = gpio_pin_configure(int_gpio_dev, config->int_gpio_pin,
+					(config->int_gpio_flags | GPIO_INPUT));
+		if (ret != 0) {
+			LOG_ERR("PCA95XX[0x%X]: failed to configure interrupt"
+				" pin %d (%d)", config->i2c_slave_addr,
+				config->int_gpio_pin, ret);
+			return ret;
+		}
+
+		/* Prepare GPIO callback for interrupt pin */
+		gpio_init_callback(&drv_data->gpio_callback,
+				   gpio_pca95xx_interrupt_callback,
+				   BIT(config->int_gpio_pin));
+		gpio_add_callback(int_gpio_dev, &drv_data->gpio_callback);
+	}
+#endif
+
 	return 0;
 }
 
@@ -501,14 +748,28 @@ static const struct gpio_pca95xx_config gpio_pca95xx_##inst##_cfg = {	\
 	.capabilities =							\
 		(DT_INST_PROP(inst, has_pud) ?			\
 			PCA_HAS_PUD : 0) |				\
+		IF_ENABLED(CONFIG_GPIO_PCA95XX_INTERRUPT, (		\
+		(DT_INST_NODE_HAS_PROP(inst, interrupt_gpios) ?		\
+			PCA_HAS_INTERRUPT : 0) |			\
+		))							\
 		0,							\
+	IF_ENABLED(CONFIG_GPIO_PCA95XX_INTERRUPT, (			\
+	IF_ENABLED(DT_INST_NODE_HAS_PROP(inst, interrupt_gpios), (	\
+	.int_gpio_port = DT_INST_GPIO_LABEL(inst, interrupt_gpios),	\
+	.int_gpio_pin = DT_INST_GPIO_PIN(inst, interrupt_gpios),	\
+	.int_gpio_flags = DT_INST_GPIO_FLAGS(inst, interrupt_gpios),	\
+	))))								\
 };									\
 									\
 static struct gpio_pca95xx_drv_data gpio_pca95xx_##inst##_drvdata = {	\
+	.reg_cache.input = 0x0,						\
 	.reg_cache.output = 0xFFFF,					\
 	.reg_cache.dir = 0xFFFF,					\
 	.reg_cache.pud_en = 0x0,					\
 	.reg_cache.pud_sel = 0xFFFF,					\
+	IF_ENABLED(CONFIG_GPIO_PCA95XX_INTERRUPT, (			\
+	.interrupt_active = false,					\
+	))								\
 };									\
 									\
 DEVICE_AND_API_INIT(gpio_pca95xx_##inst,				\
diff --git a/dts/bindings/gpio/nxp,pca95xx.yaml b/dts/bindings/gpio/nxp,pca95xx.yaml
index 50b64feecf5..4039f823161 100644
--- a/dts/bindings/gpio/nxp,pca95xx.yaml
+++ b/dts/bindings/gpio/nxp,pca95xx.yaml
@@ -16,6 +16,11 @@ properties:
       required: false
       description: Supports pull-up/pull-down
 
+    interrupt-gpios:
+      type: phandle-array
+      required: false
+      description: Interrupt GPIO pin (active-low open-drain)
+
     "#gpio-cells":
       const: 2