diff --git a/drivers/serial/Kconfig.ns16550 b/drivers/serial/Kconfig.ns16550
index 1c97a08637e..594216092e7 100644
--- a/drivers/serial/Kconfig.ns16550
+++ b/drivers/serial/Kconfig.ns16550
@@ -60,16 +60,6 @@ config UART_NS16550_ACCESS_WORD_ONLY
 	  16550 (DesignWare UART) only allows word access, byte access will raise
 	  exception.
 
-config UART_NS16550_PARENT_INIT_LEVEL
-	bool "Boot level based on parent node"
-	default y if ACPI
-	help
-	  Boot level based on parent node (PCI or no PCI device). Some platforms the
-	  PCI bus driver depends on ACPI sub system to retrieve platform information
-	  such as interrupt routing information. But ACPI sub system currently support
-	  only post kernel and hence such platforms the UART driver instance init
-	  should be invoked only post kernel in case parent node is PCI.
-
 config UART_NS16550_TI_K3
 	bool "Add support for NS16550 variant specific to TI K3 SoCs"
 	help
diff --git a/drivers/serial/uart_ns16550.c b/drivers/serial/uart_ns16550.c
index a41cdca7843..3f64d83cf36 100644
--- a/drivers/serial/uart_ns16550.c
+++ b/drivers/serial/uart_ns16550.c
@@ -1423,8 +1423,7 @@ static const struct uart_driver_api uart_ns16550_driver_api = {
 	};                                                                           \
 	DEVICE_DT_INST_DEFINE(n, &uart_ns16550_init, NULL,                           \
 			      &uart_ns16550_dev_data_##n, &uart_ns16550_dev_cfg_##n, \
-			      COND_CODE_1(CONFIG_UART_NS16550_PARENT_INIT_LEVEL,     \
-					  (POST_KERNEL), (PRE_KERNEL_1)),            \
+			      PRE_KERNEL_1,            \
 			      CONFIG_SERIAL_INIT_PRIORITY,                           \
 			      &uart_ns16550_driver_api);                             \
 	UART_NS16550_PCIE_IRQ_FUNC_DEFINE(n)