diff --git a/soc/arm/st_stm32/common/arm_mpu_mem_cfg.h b/soc/arm/st_stm32/common/arm_mpu_mem_cfg.h
index ca0a373577d..c48e59c89eb 100644
--- a/soc/arm/st_stm32/common/arm_mpu_mem_cfg.h
+++ b/soc/arm/st_stm32/common/arm_mpu_mem_cfg.h
@@ -73,6 +73,10 @@
 #define REGION_SRAM_0_SIZE REGION_256K
 #define REGION_SRAM_1_START 0x40000
 #define REGION_SRAM_1_SIZE REGION_128K
+#elif CONFIG_SRAM_SIZE == 640
+#define REGION_SRAM_0_SIZE REGION_512K
+#define REGION_SRAM_1_START 0x80000
+#define REGION_SRAM_1_SIZE REGION_128K
 #else
 #error "Unsupported configuration"
 #endif