diff --git a/drivers/bluetooth/hci/hci_ambiq.c b/drivers/bluetooth/hci/hci_ambiq.c
index 9428594980d..daaf943dca5 100644
--- a/drivers/bluetooth/hci/hci_ambiq.c
+++ b/drivers/bluetooth/hci/hci_ambiq.c
@@ -85,6 +85,18 @@ static inline int bt_spi_transceive(void *tx, uint32_t tx_len, void *rx, uint32_
 	spi_tx_buf.len = (size_t)tx_len;
 	spi_rx_buf.buf = rx;
 	spi_rx_buf.len = (size_t)rx_len;
+
+	/* Before sending packet to controller the host needs to poll the status of
+	 * controller to know it's ready, or before reading packets from controller
+	 * the host needs to get the payload size of coming packets by sending specific
+	 * command and putting the status or size to the rx buffer, the CS should be
+	 * held at this moment to continue to send or receive packets.
+	 */
+	if (tx_len && rx_len) {
+		spi_cfg.operation |= SPI_HOLD_ON_CS;
+	} else {
+		spi_cfg.operation &= ~SPI_HOLD_ON_CS;
+	}
 	return spi_transceive(spi_dev, &spi_cfg, &spi_tx, &spi_rx);
 }