diff --git a/samples/subsys/fs/littlefs/Kconfig b/samples/subsys/fs/littlefs/Kconfig
index d98d95ca62b..3ba067fb0fd 100644
--- a/samples/subsys/fs/littlefs/Kconfig
+++ b/samples/subsys/fs/littlefs/Kconfig
@@ -17,6 +17,8 @@ choice
 config APP_LITTLEFS_STORAGE_FLASH
 	bool "Use flash memory backend"
 
+config APP_LITTLEFS_STORAGE_BLK_SDMMC
+	bool "Use block device (e.g. SD MMC) backend"
 endchoice
 
 source "Kconfig.zephyr"
diff --git a/samples/subsys/fs/littlefs/README.rst b/samples/subsys/fs/littlefs/README.rst
index b2918eeca20..a4ff2b7b224 100644
--- a/samples/subsys/fs/littlefs/README.rst
+++ b/samples/subsys/fs/littlefs/README.rst
@@ -19,6 +19,9 @@ Other information about the file system is also displayed.
 Requirements
 ************
 
+Flash memory device
+-------------------
+
 The partition labeled "storage" will be used for the file system; see
 :ref:`flash_map_api`.  If that area does not already have a
 compatible littlefs file system its contents will be replaced by an
@@ -38,15 +41,57 @@ After the file system is mounted you'll also see::
 This error is also normal for Zephyr not finding a file (the boot count,
 in this case).
 
+Block device (e.g. SD card)
+---------------------------
+
+One needs to prepare the SD card with littlefs file system on
+the host machine with the `lfs`_ program.
+
+.. _lfs:
+   https://www.thevtool.com/mounting-littlefs-on-linux-machine/
+
+.. code-block:: console
+
+   sudo chmod a+rw /dev/sda
+   lfs -d -s -f --read_size=512 --prog_size=512 --block_size=512 --cache_size=512 --lookahead_size=8192 --format /dev/sda
+   lfs -d -s -f --read_size=512 --prog_size=512 --block_size=512 --cache_size=512 --lookahead_size=8192 /dev/sda ./mnt_littlefs
+   cd ./mnt_littlefs
+   echo -en '\x01' > foo.txt
+   cd -
+   fusermount -u ./mnt_littlefs
+
+
 Building and Running
 ********************
 
+Flash memory device
+-------------------
+
 This example should work on any board that provides a "storage"
 partition.  Two tested board targets are described below.
 
 You can set ``CONFIG_APP_WIPE_STORAGE`` to force the file system to be
 recreated.
 
+Block device (e.g. SD card)
+---------------------------
+
+This example has been devised and initially tested on :ref:`Nucleo H743ZI <nucleo_h743zi_board>`
+board. It can be also run on any other board with SD card connected to it.
+
+To build the test:
+
+.. zephyr-app-commands::
+   :zephyr-app: samples/subsys/fs/littlefs
+   :board: nucleo_h743zi
+   :goals: build flash
+   :gen-args: -DCONF_FILE=prj_blk.conf
+   :compact:
+
+One can also set ``CONFIG_SDMMC_VOLUME_NAME`` to provide the mount point name
+for `littlefs` file system block device.
+
+
 NRF52840 Development Kit
 ========================
 
diff --git a/samples/subsys/fs/littlefs/boards/nucleo_h743zi.overlay b/samples/subsys/fs/littlefs/boards/nucleo_h743zi.overlay
index 338dc605747..43be6063c67 100644
--- a/samples/subsys/fs/littlefs/boards/nucleo_h743zi.overlay
+++ b/samples/subsys/fs/littlefs/boards/nucleo_h743zi.overlay
@@ -1,10 +1,19 @@
 /*
- * Copyright (c) 2021 Lukasz Majewski, DENX Software Engineering GmbH
+ * Copyright (c) 2022 Lukasz Majewski, DENX Software Engineering GmbH
  *
  * SPDX-License-Identifier: Apache-2.0
  */
 /delete-node/ &storage_partition;
 
+&sdmmc1 {
+	status = "okay";
+	pinctrl-0 = <&sdmmc1_d0_pc8
+		     &sdmmc1_ck_pc12
+		     &sdmmc1_cmd_pd2>;
+
+	pinctrl-names = "default";
+};
+
 &quadspi {
 	pinctrl-0 = <&quadspi_clk_pf10 &quadspi_bk2_ncs_pc11
 		     &quadspi_bk2_io0_pe7 &quadspi_bk2_io1_pe8
diff --git a/samples/subsys/fs/littlefs/boards/nucleo_h743zi_blk.conf b/samples/subsys/fs/littlefs/boards/nucleo_h743zi_blk.conf
new file mode 100644
index 00000000000..f6a5fde1757
--- /dev/null
+++ b/samples/subsys/fs/littlefs/boards/nucleo_h743zi_blk.conf
@@ -0,0 +1,9 @@
+#
+# Copyright (c) 2022 Lukasz Majewski, DENX Software Engineering GmbH
+#
+# SPDX-License-Identifier: Apache-2.0
+#
+CONFIG_MAIN_STACK_SIZE=2048
+CONFIG_MINIMAL_LIBC_MALLOC_ARENA_SIZE=8192
+
+CONFIG_FS_LITTLEFS_FC_HEAP_SIZE=8192
diff --git a/samples/subsys/fs/littlefs/prj_blk.conf b/samples/subsys/fs/littlefs/prj_blk.conf
new file mode 100644
index 00000000000..50fdcdf9a94
--- /dev/null
+++ b/samples/subsys/fs/littlefs/prj_blk.conf
@@ -0,0 +1,26 @@
+#
+# Copyright (c) 2022 Lukasz Majewski, DENX Software Engineering GmbH
+#
+# SPDX-License-Identifier: Apache-2.0
+#
+
+CONFIG_DISK_ACCESS=y
+CONFIG_DISK_DRIVERS=y
+CONFIG_DISK_DRIVER_SDMMC=y
+
+CONFIG_DEBUG=y
+CONFIG_LOG=y
+CONFIG_LOG_MODE_MINIMAL=y
+
+CONFIG_FLASH=y
+CONFIG_FLASH_MAP=y
+CONFIG_FLASH_PAGE_LAYOUT=y
+
+CONFIG_FILE_SYSTEM=y
+CONFIG_FILE_SYSTEM_LITTLEFS=y
+
+CONFIG_FS_LITTLEFS_BLK_DEV=y
+CONFIG_APP_LITTLEFS_STORAGE_BLK_SDMMC=y
+
+CONFIG_NOCACHE_MEMORY=y
+CONFIG_SDMMC_STM32_HWFC=y
diff --git a/samples/subsys/fs/littlefs/src/main.c b/samples/subsys/fs/littlefs/src/main.c
index 7f0e71d8072..714f21ef868 100644
--- a/samples/subsys/fs/littlefs/src/main.c
+++ b/samples/subsys/fs/littlefs/src/main.c
@@ -308,6 +308,27 @@ static int littlefs_mount(struct fs_mount_t *mp)
 }
 #endif /* CONFIG_APP_LITTLEFS_STORAGE_FLASH */
 
+#ifdef CONFIG_APP_LITTLEFS_STORAGE_BLK_SDMMC
+struct fs_littlefs lfsfs;
+static struct fs_mount_t __mp = {
+	.type = FS_LITTLEFS,
+	.fs_data = &lfsfs,
+	.flags = FS_MOUNT_FLAG_USE_DISK_ACCESS,
+};
+struct fs_mount_t *mp = &__mp;
+
+static int littlefs_mount(struct fs_mount_t *mp)
+{
+	static const char *disk_mount_pt = "/"CONFIG_SDMMC_VOLUME_NAME":";
+	static const char *disk_pdrv = CONFIG_SDMMC_VOLUME_NAME;
+
+	mp->storage_dev = (void *)disk_pdrv;
+	mp->mnt_point = disk_mount_pt;
+
+	return fs_mount(mp);
+}
+#endif /* CONFIG_APP_LITTLEFS_STORAGE_BLK_SDMMC */
+
 void main(void)
 {
 	char fname1[MAX_PATH_LEN];