diff --git a/drivers/serial/uart_stm32.c b/drivers/serial/uart_stm32.c
index 9243b10d7e7..8cf10e6a151 100644
--- a/drivers/serial/uart_stm32.c
+++ b/drivers/serial/uart_stm32.c
@@ -23,6 +23,7 @@
 #include <zephyr/drivers/clock_control.h>
 #include <zephyr/pm/policy.h>
 #include <zephyr/pm/device.h>
+#include <zephyr/pm/device_runtime.h>
 
 #ifdef CONFIG_UART_ASYNC_API
 #include <zephyr/drivers/dma/dma_stm32.h>
@@ -671,6 +672,11 @@ static void uart_stm32_poll_out_visitor(const struct device *dev, void *out, pol
 		 */
 		uart_stm32_pm_policy_state_lock_get(dev);
 
+		/* Resume device if needed before enabling IT */
+		if (pm_device_runtime_is_enabled(dev)) {
+			(void)pm_device_runtime_get(dev);
+		}
+
 		/* Enable TC interrupt so we can release suspend
 		 * constraint when done
 		 */
@@ -1263,6 +1269,11 @@ static void uart_stm32_isr(const struct device *dev)
 		async_evt_tx_done(data);
 
 #ifdef CONFIG_PM
+		/* Device can now be released */
+		if (pm_device_runtime_is_enabled(dev)) {
+			(void)pm_device_runtime_put(dev);
+		}
+
 		uart_stm32_pm_policy_state_lock_put(dev);
 #endif
 	} else if (LL_USART_IsEnabledIT_RXNE(config->usart) &&