diff --git a/drivers/usb/device/usb_dc_stm32.c b/drivers/usb/device/usb_dc_stm32.c
index 75ce9442f8e..ad9c6ac520c 100644
--- a/drivers/usb/device/usb_dc_stm32.c
+++ b/drivers/usb/device/usb_dc_stm32.c
@@ -276,14 +276,16 @@ static int usb_dc_stm32_clock_enable(void)
 	 */
 	LL_AHB1_GRP1_DisableClockSleep(LL_AHB1_GRP1_PERIPH_USB1OTGHSULPI);
 #endif
-#else
+#else /* DT_HAS_COMPAT_STATUS_OKAY(st_stm32_usbphyc) */
+#if !USB_OTG_HS_ULPI_PHY
 	/* Disable ULPI interface (for external high-speed PHY) clock in low
 	 * power mode. It is disabled by default in run power mode, no need to
 	 * disable it.
 	 */
 	LL_AHB1_GRP1_DisableClockLowPower(LL_AHB1_GRP1_PERIPH_OTGHSULPI);
-#endif
-#endif
+#endif /* USB_OTG_HS_ULPI_PHY */
+#endif /* DT_HAS_COMPAT_STATUS_OKAY(st_stm32_usbphyc) */
+#endif /* DT_HAS_COMPAT_STATUS_OKAY(st_stm32_otghs) */
 
 	return 0;
 }
diff --git a/drivers/usb/udc/udc_stm32.c b/drivers/usb/udc/udc_stm32.c
index e11228619b8..9b912f792c9 100644
--- a/drivers/usb/udc/udc_stm32.c
+++ b/drivers/usb/udc/udc_stm32.c
@@ -988,14 +988,16 @@ static int priv_clock_enable(void)
 	 */
 	LL_AHB1_GRP1_DisableClockSleep(LL_AHB1_GRP1_PERIPH_USB2OTGHSULPI);
 #endif
-#else
+#else /* DT_HAS_COMPAT_STATUS_OKAY(st_stm32_usbphyc) */
+#if !USB_OTG_HS_ULPI_PHY
 	/* Disable ULPI interface (for external high-speed PHY) clock in low
 	 * power mode. It is disabled by default in run power mode, no need to
 	 * disable it.
 	 */
 	LL_AHB1_GRP1_DisableClockLowPower(LL_AHB1_GRP1_PERIPH_OTGHSULPI);
-#endif
-#endif
+#endif /* USB_OTG_HS_ULPI_PHY */
+#endif /* DT_HAS_COMPAT_STATUS_OKAY(st_stm32_usbphyc) */
+#endif /* DT_HAS_COMPAT_STATUS_OKAY(st_stm32_otghs) */
 
 	return 0;
 }